2-(3-aminophenylamino)-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one

• 常用名: 2-(3-aminophenylamino)-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one
• 英文名: 2-(3-aminophenylamino)-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one
• CAS号: 648903-76-8
• 分子量: 412.3
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₅Cl₂N₅O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-(3-aminophenylamino)-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one

物理化学性质

• 分子式: C₂₀H₁₅Cl₂N₅O
• 分子量: 412.3
• InChIKey: LPJDSINAEJVSNX-UHFFFAOYSA-N
• SMILES: Cn1c(=O)c(-c2c(Cl)cccc2Cl)cc2cnc(Nc3cccc(N)c3)nc21

靶点实验

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实验名称：Cytotoxicity against Philadelphia chromosome positive human Kasumi-4 cells by Alamar ... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1050607

实验名称：Inhibition of human recombinant Abl 来源：ChEMBL 靶标：Tyrosine-protein kinase ABL1 External Id：CHEMBL1050608

实验名称：Inhibition of recombinant c-Abl after 30 mins 来源：ChEMBL 靶标：Tyrosine-protein kinase ABL1 External Id：CHEMBL1227835

实验名称：Selectivity ratio of IC50 for human recombinant PDGFR to IC50 for human recombinant A... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1050615

实验名称：Selectivity ratio of IC50 for human recombinant Src to IC50 for human recombinant Abl 来源：ChEMBL 靶标：N/A External Id：CHEMBL1050616

实验名称：Inhibition of human recombinant C-Kit 来源：ChEMBL 靶标：Mast/stem cell growth factor receptor Kit External Id：CHEMBL1050613

实验名称：Selectivity ratio of IC50 for human recombinant P38alpha to IC50 for human recombinan... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1050614

实验名称：Inhibition of human recombinant VEGFR 来源：ChEMBL 靶标：N/A External Id：CHEMBL1050611

实验名称：Inhibition of human recombinant Src 来源：ChEMBL 靶标：Proto-oncogene tyrosine-protein kinase Src External Id：CHEMBL1050612

实验名称：Inhibition of human recombinant P38alpha 来源：ChEMBL 靶标：Mitogen-activated protein kinase 14 External Id：CHEMBL1050609

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