2,4-Difluoro-5-(5-isopropyl-6-(5-(methylsulfonylmethyl)-1,3,4-oxadiazol-2-YL)pyrrolo[2,1-F][1,2,4]triazin-4-ylamino)-N-methoxybenzamide

• 常用名: 2,4-Difluoro-5-(5-isopropyl-6-(5-(methylsulfonylmethyl)-1,3,4-oxadiazol-2-YL)pyrrolo[2,1-F][1,2,4]triazin-4-ylamino)-N-methoxybenzamide
• 英文名: 2,4-Difluoro-5-(5-isopropyl-6-(5-(methylsulfonylmethyl)-1,3,4-oxadiazol-2-YL)pyrrolo[2,1-F][1,2,4]triazin-4-ylamino)-N-methoxybenzamide
• CAS号: 658085-06-4
• 分子量: 521.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₁F₂N₇O₅S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2,4-Difluoro-5-(5-isopropyl-6-(5-(methylsulfonylmethyl)-1,3,4-oxadiazol-2-YL)pyrrolo[2,1-F][1,2,4]triazin-4-ylamino)-N-methoxybenzamide

物理化学性质

• 分子式: C₂₁H₂₁F₂N₇O₅S
• 分子量: 521.5
• InChIKey: PLKAJXMYXBXIGX-UHFFFAOYSA-N
• SMILES: CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(CS(C)(=O)=O)o4)c(C(C)C)c23)c(F)cc1F

靶点实验

查看更多实验

实验名称：Inhibition of human fibroblast growth factor receptor 1 来源：ChEMBL 靶标：Fibroblast growth factor receptor 1 External Id：CHEMBL829448

实验名称：Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferation 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 3 External Id：CHEMBL837258

实验名称：Inhibition of human vascular endothelial growth factor receptor 2 kinase activity 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 2 External Id：CHEMBL829589

实验名称：Tumor growth inhibition determined after oral administration of 100 mg/kg/day compoun... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL835303

实验名称：Plasma level after 1 hour of oral administration of 50 mg/kg compound in mouse 来源：ChEMBL 靶标：N/A External Id：CHEMBL838445

实验名称：Tumor growth inhibition determined after oral administration of 60 mg/kg/day compound... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL831568

实验名称：Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferation 来源：ChEMBL 靶标：Fibroblast growth factor receptor 4 External Id：CHEMBL825076

实验名称：Plasma level after 4 hours of oral administration of 50 mg/kg compound in mouse 来源：ChEMBL 靶标：N/A External Id：CHEMBL838446

共8条，当前第1页，共1页

1