4-(3H-imidazo[4,5-c]pyridin-2-yl)-1,3-thiazole

• 常用名: 4-(3H-imidazo[4,5-c]pyridin-2-yl)-1,3-thiazole
• 英文名: 4-(3H-imidazo[4,5-c]pyridin-2-yl)-1,3-thiazole
• CAS号: 65911-26-4
• 分子量: 202.23600
• 密度: N/A
• 沸点: N/A
• 分子式: C₉H₆N₄S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-(3H-imidazo[4,5-c]pyridin-2-yl)-1,3-thiazole

物理化学性质

• 分子式: C₉H₆N₄S
• 分子量: 202.23600
• 精确质量: 202.03100
• PSA: 82.70000
• LogP: 2.08140
• InChIKey: ZLDMVYZYJDSJCY-UHFFFAOYSA-N
• SMILES: c1cc2nc(-c3cscn3)[nH]c2cn1

靶点实验

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实验名称：Inhibition of NLRP3 inflammasome activation in LPS-stimulated human THP1 cells assess... 来源：ChEMBL 靶标：NACHT, LRR and PYD domains-containing protein 3 External Id：CHEMBL4324159

实验名称：Inhibition of LPS/ATP induced IL-1beta release in human THP-1 cells at 10 uM pretreat... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5634866

实验名称：Cytotoxicity against HUVEC assessed as inhibition of cell proliferation rate at 10 uM... 来源：ChEMBL 靶标：HUVEC External Id：CHEMBL3587104

实验名称：Inhibition of Mn2+ loaded MetAP expressed in Escherichia coli at upto 10 uM 来源：ChEMBL 靶标：Methionine aminopeptidase External Id：CHEMBL865845

实验名称：Cytotoxicity against HUVEC assessed as inhibition of cell proliferation rate at 100 u... 来源：ChEMBL 靶标：HUVEC External Id：CHEMBL3587105

实验名称：Inhibition of Co2+ loaded MetAP expressed in Escherichia coli 来源：ChEMBL 靶标：Methionine aminopeptidase External Id：CHEMBL865844

实验名称：Anti-inflammatory activity in human THP-1 cells assessed as inhibition in IL-1beta re... 来源：ChEMBL 靶标：THP-1 External Id：CHEMBL5234787

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英文别名

• 1H-Imidazo[4,5-c]pyridine,2-(4-thiazolyl)
• 8-(4'-Thiazolyl)-1-imidazo<4',5'-c>pyridin
• 2-thiazol-4-yl-1(3)H-imidazo[4,5-c]pyridine