8-({6-[4-(Trifluoromethyl)phenyl]pyrimidin-4-yl}oxy)quinolin-2-amine

• 常用名: 8-({6-[4-(Trifluoromethyl)phenyl]pyrimidin-4-yl}oxy)quinolin-2-amine
• 英文名: 8-({6-[4-(Trifluoromethyl)phenyl]pyrimidin-4-yl}oxy)quinolin-2-amine
• CAS号: 659729-10-9
• 分子量: 382.3
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₃F₃N₄O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 8-({6-[4-(Trifluoromethyl)phenyl]pyrimidin-4-yl}oxy)quinolin-2-amine

物理化学性质

• 分子式: C₂₀H₁₃F₃N₄O
• 分子量: 382.3
• InChIKey: XEBBMEXBEQLSSM-UHFFFAOYSA-N
• SMILES: Nc1ccc2cccc(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2n1

靶点实验

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实验名称：Metabolic stability in human liver microsomes assessed as clearance 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL890312

实验名称：Metabolic stability in rat liver microsomes assessed as clearance 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL890313

实验名称：Antagonist activity at rat TRPV1 expressed in CHO cells assessed as inhibition of cap... 来源：ChEMBL 靶标：Transient receptor potential cation channel subfamily V member 1 External Id：CHEMBL890307

实验名称：Antagonist activity at rat TRPV1 expressed in CHO cells assessed as inhibition of aci... 来源：ChEMBL 靶标：Transient receptor potential cation channel subfamily V member 1 External Id：CHEMBL890308

实验名称：Capsaicin Antagonist Assay from Article 10.1021/jm070190p: "Novel vanilloid receptor-... 来源：BindingDB 靶标：N/A External Id：BindingDB_2434_1

实验名称：In vivo clearance in Sprague-Dawley rat at 1 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL890314

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