7-Methyl-2-(4-morpholinyl)-9-[1-[[2-(2H-tetrazol-5-yl)phenyl]amino]ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one

• 常用名: 7-Methyl-2-(4-morpholinyl)-9-[1-[[2-(2H-tetrazol-5-yl)phenyl]amino]ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one
• 英文名: 7-Methyl-2-(4-morpholinyl)-9-[1-[[2-(2H-tetrazol-5-yl)phenyl]amino]ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one
• CAS号: 663620-73-3
• 分子量: 432.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₂₄N₈O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 7-Methyl-2-(4-morpholinyl)-9-[1-[[2-(2H-tetrazol-5-yl)phenyl]amino]ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one

物理化学性质

• 分子式: C₂₂H₂₄N₈O₂
• 分子量: 432.5
• InChIKey: VOKGKARHNCQWAZ-UHFFFAOYSA-N
• SMILES: Cc1cc(C(C)Nc2ccccc2-c2nn[nH]n2)c2nc(N3CCOCC3)cc(=O)n2c1

靶点实验

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实验名称：Inhibition of human recombinant PI3Kbeta assessed as PIP3 production by AlphaScreen a... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform External Id：CHEMBL3368174

实验名称：Inhibition of human recombinant PI3Kalpha assessed as PIP3 production by AlphaScreen ... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform External Id：CHEMBL3368175

实验名称：Lipophilicity, log D of the compound at pH 7.4 by HPLC method 来源：ChEMBL 靶标：N/A External Id：CHEMBL3368178

实验名称：Apparent permeability across apical to basolateral side of human Caco2 cells at 10 uM... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3368176

实验名称：Intrinsic clearance in human hepatocytes at 2 uM by LCMS analysis 来源：ChEMBL 靶标：Hepatocyte External Id：CHEMBL3368177

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