9-(4-甲氧基-2,3,6-三甲基苯基)-3,7-二甲基-2,4,6,8-丁烯酸

更新时间：2025-08-26 00:03:31

9-(4-甲氧基-2,3,6-三甲基苯基)-3,7-二甲基-2,4,6,8-丁烯酸结构式	常用名	9-(4-甲氧基-2,3,6-三甲基苯基)-3,7-二甲基-2,4,6,8-丁烯酸	英文名	13-cis-Acitretin
	CAS号	69427-46-9	分子量	326.429
	密度	1.1±0.1 g/cm3	沸点	521.3±38.0 °C at 760 mmHg
	分子式	C₂₁H₂₆O₃	熔点	228-230ºC
	MSDS	N/A	闪点	180.3±20.3 °C

用途

Isoacitretin is an oral retinoid effective in the treatment of psoriasis.

中文名	9-(4-甲氧基-2,3,6-三甲基苯基)-3,7-二甲基-2,4,6,8-丁烯酸
英文名	13-cis Acitretin
英文别名	更多

密度	1.1±0.1 g/cm3
沸点	521.3±38.0 °C at 760 mmHg
熔点	228-230ºC
分子式	C₂₁H₂₆O₃
分子量	326.429
闪点	180.3±20.3 °C
精确质量	326.188202
PSA	46.53000
LogP	5.73
InChIKey	IHUNBGSDBOWDMA-UGOGCBOOSA-N
SMILES	COc1cc(C)c(C=CC(C)=CC=CC(C)=CC(=O)O)c(C)c1C
蒸汽压	0.0±1.4 mmHg at 25°C
折射率	1.570
储存条件	Amber Vial, -80°C Freezer

危险品运输编码	NONH for all modes of transport

Comparative effectiveness of less commonly used systemic monotherapies and common combination therapies for moderate to severe psoriasis in the clinical setting.

J. Am. Acad. Dermatol. 71(6) , 1167-75, (2014)

The effectiveness of psoriasis therapies in real-world settings remains relatively unknown.We sought to compare the effectiveness of less commonly used systemic therapies and commonly used combination...

Acitretin exhibits inhibitory effects towards UDP-glucuronosyltransferase (UGT)1A9-mediated 4-methylumbelliferone (4-MU) and propofol glucuronidation reaction.

Pharmazie 68(6) , 449-52, (2013)

The present study aimed to evaluate the potential risk of drug-drug interactions associated with acitretin which is a drug for therapy of psoriasis approved by the Food and Drug Administration (FDA). ...

IgA pemphigus: case series with emphasis on therapeutic response.

J. Am. Acad. Dermatol. 70(1) , 200-1, (2014)

Soriatane

9-(4-methoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid

9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid

(2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid

(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid

9-(4-Isopropyl-phenyl)-guanin

Neo-Tigasone

Acetretinate

(all-E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid

Neotigason

2-amino-9-(4-isopropyl-phenyl)-1,9-dihydro-purin-6-one

Acitretin

(2E,4E,6E,8E)-3,7-dimethyl-9-[2,3,6-trimethyl-4-(methyloxy)phenyl]nona-2,4,6,8-tetraenoic acid

all-trans-acitretin

SNGP-201-04-E06

9-(4-甲氧基-2,3,6-三甲基苯基)-3,7-二甲基-2,4,6,8-丁烯酸

用途

名称

物理化学性质

安全信息

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英文别名

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