5-氨基-1-(2-吡啶基)-1H-吡唑-4-羧酸乙酯结构式
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常用名 | 5-氨基-1-(2-吡啶基)-1H-吡唑-4-羧酸乙酯 | 英文名 | ETHYL5-AMINO-1-(PYRIDIN-2-YL)-1H-PYRAZOLE-4-CARBOXYLATE |
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| CAS号 | 69722-29-8 | 分子量 | 232.23900 | |
| 密度 | 1.34g/cm3 | 沸点 | 410.3ºC at 760mmHg | |
| 分子式 | C11H12N4O2 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | 202ºC |
| 中文名 | 5-氨基-1-(2-吡啶基)-1H-吡唑-4-羧酸乙酯 |
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| 英文名 | ethyl 5-amino-1-pyridin-2-ylpyrazole-4-carboxylate |
| 英文别名 | 更多 |
| 密度 | 1.34g/cm3 |
|---|---|
| 沸点 | 410.3ºC at 760mmHg |
| 分子式 | C11H12N4O2 |
| 分子量 | 232.23900 |
| 闪点 | 202ºC |
| 精确质量 | 232.09600 |
| PSA | 83.03000 |
| LogP | 1.60740 |
| InChIKey | UPTKQJLYDVZTKJ-UHFFFAOYSA-N |
| SMILES | CCOC(=O)c1cnn(-c2ccccn2)c1N |
| 折射率 | 1.639 |
| 储存条件 | 2-8°C,避光,保存于惰性气体中 |
| 海关编码 | 2933990090 |
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~73%
5-氨基-1-(2-吡啶基)-... 69722-29-8 |
| 文献:Takeda Chemical Industries, Ltd. Patent: EP1380296 A1, 2004 ; |
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~61%
5-氨基-1-(2-吡啶基)-... 69722-29-8 |
| 文献:Das, Jagabandhu; Moquin, Robert V.; Dyckman, Alaric J.; Li, Tianle; Pitt, Sidney; Zhang, Rosemary; Shen, Ding Ren; McIntyre, Kim W.; Gillooly, Kathleen; Doweyko, Arthur M.; Newitt, John A.; Sack, John S.; Zhang, Hongjian; Kiefer, Susan E.; Kish, Kevin; McKinnon, Murray; Barrish, Joel C.; Dodd, John H.; Schieven, Gary L.; Leftheris, Katerina Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 23 p. 6886 - 6889 |
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~75%
5-氨基-1-(2-吡啶基)-... 69722-29-8 |
| 文献:Frigola; Colombo; Pares; Martinez; Sagarra; Roser European Journal of Medicinal Chemistry, 1989 , vol. 24, # 4 p. 435 - 445 |
| 5-氨基-1-(2-吡啶基)-1H-吡唑-4-羧酸乙酯上游产品 4 | |
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| 5-氨基-1-(2-吡啶基)-1H-吡唑-4-羧酸乙酯下游产品 1 | |
| 海关编码 | 2933990090 |
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| 中文概述 | 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期 |
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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实验名称:Primary cell-based high-throughput screening assay for identification of compounds th...
来源:Johns Hopkins Ion Channel Center
靶标:regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id:JHICC_RGS_Act_HTS
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实验名称:Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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实验名称:QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源:The Scripps Research Institute Molecular Screening Center
靶标:disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id:ADAM17_INH_QFRET_1536_1X%INH PRUN
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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实验名称:High throughput fluorescence intensity-based biochemical assay to screen for small mo...
来源:University of Pittsburgh Molecular Library Screening Center
靶标:furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id:MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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实验名称:Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
来源:Broad Institute
靶标:FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id:2147-01_Inhibitor_SinglePoint_HTS_Activity
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实验名称:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
来源:Broad Institute
靶标:N/A
External Id:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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实验名称:Fluorescence polarization-based biochemical high throughput primary assay to identify...
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id:SIAE_INH_FP_1536_1X%INH PRUN
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| 5-amino-4-carboxyethyl-1-(2-pyridyl)-1H-pyrazole |
| ethyl 5-amino-1-(pyridin-2-yl)-1H-pyrazole-4-carboxylate |
| ethyl 5-amino-1-(2-pyridyl)-1H-pyrazole-4-carboxylate |
| ethyl 5-amino-1-(2-pyridinyl)-1H-pyrazole-4-carboxylate |
| 5-amino-1-pyridin-2-yl-1H-pyrazole-4-carboxylic acid ethyl ester |
| 5-amino-1-(2-pyridinyl)-1H-pyrazole-4-carboxylic acid,ethyl ester |