2,4-Pteridinediamine, 6-((1-naphthalenylamino)-methyl)

• 常用名: 2,4-Pteridinediamine, 6-((1-naphthalenylamino)-methyl)
• 英文名: 2,4-Pteridinediamine, 6-((1-naphthalenylamino)-methyl)
• CAS号: 70583-39-0
• 分子量: 317.34800
• 密度: 1.474g/cm3
• 沸点: 642.1ºC at 760 mmHg
• 分子式: C₁₇H₁₅N₇
• 熔点: N/A
• 闪点: 342.2ºC

名称

• 英文名: 6-[(naphthalen-1-ylamino)methyl]pteridine-2,4-diamine

物理化学性质

• 密度: 1.474g/cm3
• 沸点: 642.1ºC at 760 mmHg
• 分子式: C₁₇H₁₅N₇
• 分子量: 317.34800
• 闪点: 342.2ºC
• 精确质量: 317.13900
• PSA: 115.63000
• LogP: 3.58490
• InChIKey: QVHFSGMRVQZGMC-UHFFFAOYSA-N
• SMILES: Nc1nc(N)c2nc(CNc3cccc4ccccc34)cnc2n1
• 折射率: 1.858

靶点实验

查看更多实验

实验名称：Inhibition of recombinant Trypanosoma brucei PTR1 expressed in Escherichia coli BL21 ... 来源：ChEMBL 靶标：Pteridine reductase, putative External Id：CHEMBL5148453

实验名称：Inhibition of CYP2D6 (unknown origin) expressed in baculovirus-infected insect cells ... 来源：ChEMBL 靶标：Cytochrome P450 2D6 External Id：CHEMBL5148470

实验名称：Inhibition of CYP3A4 (unknown origin) expressed in baculovirus-infected insect cells ... 来源：ChEMBL 靶标：Cytochrome P450 3A4 External Id：CHEMBL5148471

实验名称：Mitochondrial toxicity in human 786-0 cells at 10 uM incubated with compound for 6 hr... 来源：ChEMBL 靶标：786-0 External Id：CHEMBL5148472

实验名称：Cytotoxicity against human A549 cells at 10 uM measured after 48 hrs by Celltiter-Glo... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5148473

实验名称：Inhibition of hERG potassium channel at 10 uM by fluorescence polarization assay rela... 来源：ChEMBL 靶标：Potassium voltage-gated channel subfamily H member 2 External Id：CHEMBL5148466

实验名称：Inhibition of CYP1A2 (unknown origin) expressed in baculovirus-infected insect cells ... 来源：ChEMBL 靶标：Cytochrome P450 1A2 External Id：CHEMBL5148467

实验名称：Inhibition of CYP2C9 (unknown origin) expressed in baculovirus-infected insect cells ... 来源：ChEMBL 靶标：Cytochrome P450 2C9 External Id：CHEMBL5148468

实验名称：Inhibition of CYP2C19 (unknown origin) expressed in baculovirus-infected insect cells... 来源：ChEMBL 靶标：Cytochrome P450 2C19 External Id：CHEMBL5148469

实验名称：Selectivity index, ratio of IC50 for human DHFR to IC50 for Trypanosoma brucei PTR1 来源：ChEMBL 靶标：N/A External Id：CHEMBL5148458

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英文别名

• 2,4-Pteridinediamine,6-[(1-naphthalenylamino)-methyl]
• 6-(naphthalen-1-ylamino-methyl)-pteridine-2,4-diamine