N-[(1S)-2-[(1S,3S,5S)-3-氰基-2-氮杂双环[3.1.0]己烷-2-基]-1-(3-羟基三环[3.3.1.13,7]癸烷-1-基)-2-氧代乙基]氨基甲酸 1,1-二甲基乙酯

• 常用名: N-[(1S)-2-[(1S,3S,5S)-3-氰基-2-氮杂双环[3.1.0]己烷-2-基]-1-(3-羟基三环[3.3.1.13,7]癸烷-1-基)-2-氧代乙基]氨基甲酸 1,1-二甲基乙酯
• 英文名: N-[(1S)-2-[(1S,3S,5S)-3-Cyano-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-2-oxoethyl]carbamic acid 1,1-dimethylethyl ester
• CAS号: 709031-43-6
• 分子量: 415.526
• 密度: 1.3±0.1 g/cm3
• 沸点: 624.7±40.0 °C at 760 mmHg
• 分子式: C₂₃H₃₃N₃O₄
• 熔点: N/A
• 闪点: 331.6±27.3 °C

名称

• 中文名: N-[(1S)-2-[(1S,3S,5S)-3-氰基-2-氮杂双环[3.1.0]己烷-2-基]-1-(3-羟基三环[3.3.1.13,7]癸烷-1-基)-2-氧代乙基]氨基甲酸 1,1-二甲基乙酯
• 英文名: tert-butyl N-[2-(3-cyano-2-azabicyclo[3.1.0]hexan-2-yl)-1-(3-hydroxy-1-adamantyl)-2-oxoethyl]carbamate
• 中文别名: 沙格列汀中间体4 | N-[(1S)-2-[(1S,3S,5S)-3-氰基-2-氮杂双环[3.1.0]己烷-2-基]-1-(3-羟基三环[3.3.1.1(3,7)]癸烷-1-基)-2-氧代乙基]氨基甲酸 1,1-二甲基乙酯

物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 624.7±40.0 °C at 760 mmHg
• 分子式: C₂₃H₃₃N₃O₄
• 分子量: 415.526
• 闪点: 331.6±27.3 °C
• 精确质量: 415.247101
• PSA: 106.15000
• LogP: 1.64
• 蒸汽压: 0.0±4.1 mmHg at 25°C
• 折射率: 1.594

英文别名

• tert-butyl N-[(1S)-2-[(1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hexan-2-yl]-1-[(5R,7S)-3-hydroxy-1-adamantyl]-2-oxoethyl]carbamate
• 2-Methyl-2-propanyl [(1S)-2-[(1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxyadamantan-1-yl)-2-oxoethyl]carbamate
• L66 B6/B-H/DI A B- C 1B ITJ BQ DYMVOX1&1&1&V- DT35 DNTJ ECN &&[(S)-2-(1S,3S,5S)- Form
• N-[(1S)-2-[(1S,3S,5S)-3-Cyano-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)-2-oxoethyl]carbamic acid, 1,1-dimethylethyl ester
• 1,1-Dimethylethyl N-[(1S)-2-[(1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)-2-oxoethyl]carbamate
• (S)-N-Boc-3-hydroxyadamantylglycine-L-cis-4,5-methanoprolinenitrile
• N-[(1S)-2-[(1S,3S,5S)-3-CYANO-2-AZABICYCLO[3.1.0]HEX-2-YL]-1-(3-HYDROXYTRICYCLO[3.3.1.13,7]DEC-1-YL)-2-OXOETHYL]CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER
• (1S,3S,5S)-2-[(2S)-2-[(1,1-dimethoxy)carbonyl]amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile
• [(1S)-2-[(1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxy-tricyclo[3.3.1.13,7]dec-1-yl)-2-oxoethyl]-carbamic acid 1,1-dimethyl-ethyl ester
• Boc-saxagliptin
• Carbamic acid, N-[(1S)-2-[(1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)-2-oxoethyl]-, 1,1-dimethylethyl ester