7-Fluoro-N-(3-fluorophenyl)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide

• 常用名: 7-Fluoro-N-(3-fluorophenyl)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide
• 英文名: 7-Fluoro-N-(3-fluorophenyl)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide
• CAS号: 71886-10-7
• 分子量: 316.26
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₆H₁₀F₂N₂O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 7-Fluoro-N-(3-fluorophenyl)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide

物理化学性质

• 分子式: C₁₆H₁₀F₂N₂O₃
• 分子量: 316.26
• InChIKey: VYEFSTCOOYYNTC-UHFFFAOYSA-N
• SMILES: O=C(Nc1cccc(F)c1)c1c(O)c2ccc(F)cc2[nH]c1=O

靶点实验

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实验名称：Inhibition of PI3Kalpha in human HCT116 cells assessed as increase in PARP cleavage r... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform External Id：CHEMBL2211757

实验名称：Inhibition of PI3Kalpha H1047R mutant in human HCT116 cells assessed as inhibition of... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform External Id：CHEMBL2211758

实验名称：Inhibition of PI3Kalpha H1047R mutant in human HCT116 cells assessed as increase in P... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform External Id：CHEMBL2211756

实验名称：Inhibition of PI3Kalpha in human HCT116 cells relative to LY294002 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform External Id：CHEMBL2211761

实验名称：Inhibition of PI3Kalpha in human HCT116 cells assessed as inhibition of Akt phosphory... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform External Id：CHEMBL2211759

实验名称：Inhibition of PI3Kalpha H1047R mutant in human HCT116 cells relative to LY294002 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform External Id：CHEMBL2211760

实验名称：Selectivity index, ratio of IC50 for human HCT116 cell to IC50 for PI3Kalpha H1047R m... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL2211763

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