Z-亚丁基苯酞

• 常用名: Z-亚丁基苯酞
• 英文名: (Z)-Butylidenephthalide
• CAS号: 72917-31-8
• 分子量: 188.22
• 密度: 1.2±0.1 g/cm3
• 沸点: 328.3±41.0 °C at 760 mmHg
• 分子式: C₁₂H₁₂O₂
• 熔点: N/A
• 闪点: 135.7±25.0 °C

Z-亚丁基苯酞用途

(Z) -3-丁烯基萘酞是一种通过抑制肠道和酵母R-葡萄糖苷酶的活性(IC50=2.35 mM；Ki=4.86 mM)来降血糖的药物[1]。

Z-亚丁基苯酞名称

• 中文名: Z-亚丁基苯酞
• 英文名: 3-butylidene-(3Z)-1(3H)-Isobenzofuranone

Z-亚丁基苯酞生物活性

• 描述: (Z) -3-丁烯基萘酞是一种通过抑制肠道和酵母R-葡萄糖苷酶的活性(IC50=2.35 mM；Ki=4.86 mM)来降血糖的药物[1]。
• 相关类别:
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Fernando Brindis, et al. (Z)-3-butylidenephthalide from Ligusticum porteri , an α-glucosidase inhibitor. J Nat Prod. 2011 Mar 25;74(3):314-20.

Z-亚丁基苯酞物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 328.3±41.0 °C at 760 mmHg
• 分子式: C₁₂H₁₂O₂
• 分子量: 188.22
• 闪点: 135.7±25.0 °C
• 精确质量: 190.099380
• PSA: 26.30000
• LogP: 1.69
• InChIKey: WMBOCUXXNSOQHM-FLIBITNWSA-N
• SMILES: CCCC=C1OC(=O)c2ccccc21
• 外观性状: 油状物质
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.567
• 储存条件: 室温

Z-亚丁基苯酞靶点实验

查看更多实验

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实验名称：Antiplatelet activity in human platelet rich plasma assessed as inhibition of ADP-ind... 来源：ChEMBL 靶标：Plasma External Id：CHEMBL924387

实验名称：Adulticidal activity against female Bemisia tabaci biotype Q (sweet potato whitefly) ... 来源：ChEMBL 靶标：Bemisia tabaci External Id：CHEMBL3051989

实验名称：Antiplatelet activity in human platelet rich plasma assessed as inhibition of arachid... 来源：ChEMBL 靶标：Plasma External Id：CHEMBL924388

实验名称：Antagonist activity at rat recombinant TRPA1 overexpressed in HEK293 cells assessed a... 来源：ChEMBL 靶标：Transient receptor potential cation channel subfamily A member 1 External Id：CHEMBL2433972

实验名称：Agonist activity at rat recombinant TRPM8 overexpressed in HEK293 cells assessed as i... 来源：ChEMBL 靶标：Transient receptor potential cation channel subfamily M member 8 External Id：CHEMBL2433971

实验名称：Agonist activity at rat recombinant TRPM8 overexpressed in HEK293 cells assessed as i... 来源：ChEMBL 靶标：Transient receptor potential cation channel subfamily M member 8 External Id：CHEMBL2433970

实验名称：Antagonist activity at rat recombinant TRPM8 overexpressed in HEK293 cells assessed a... 来源：ChEMBL 靶标：Transient receptor potential cation channel subfamily M member 8 External Id：CHEMBL2433969

实验名称：Agonist activity at rat recombinant TRPA1 overexpressed in HEK293 cells assessed as i... 来源：ChEMBL 靶标：Transient receptor potential cation channel subfamily A member 1 External Id：CHEMBL2433974

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Z-亚丁基苯酞英文别名

• (Z)-Butylidenephthalide
• 1-Ethyl-1-methyl-1,1a-dihydrocyclopropa[c][2]benzofuran-3(3aH)-one