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8-Quinazolinecarbonitrile,1,4-dihydro-4,6,7-trimethyl

更新时间:2025-09-18 09:48:48

8-Quinazolinecarbonitrile,1,4-dihydro-4,6,7-trimethyl结构式
8-Quinazolinecarbonitrile,1,4-dihydro-4,6,7-trimethyl结构式
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常用名 8-Quinazolinecarbonitrile,1,4-dihydro-4,6,7-trimethyl 英文名 8-Quinazolinecarbonitrile,1,4-dihydro-4,6,7-trimethyl
CAS号 73318-20-4 分子量 199.25200
密度 1.15g/cm3 沸点 319.4ºC at 760mmHg
分子式 C12H13N3 熔点 N/A
MSDS N/A 闪点 146.9ºC

 名称

英文名 4,6,7-trimethyl-1,4-dihydroquinazoline-8-carbonitrile
英文别名 更多

 物理化学性质

密度 1.15g/cm3
沸点 319.4ºC at 760mmHg
分子式 C12H13N3
分子量 199.25200
闪点 146.9ºC
精确质量 199.11100
PSA 48.18000
LogP 2.26348
InChIKey JZZVVNQVOVKBRU-UHFFFAOYSA-N
SMILES Cc1cc2c(c(C#N)c1C)NC=NC2C
折射率 1.615

 合成线路

~81%

8-Quinazolinecarbonitrile,1,4-dihydro-4,6,7-trimethyl结构式

8-Quinazolineca...

73318-20-4

文献:Nixon Jr.; Garland; DeWitt Blanton Jr. Synthesis, 1980 , vol. No. 1, p. 56 - 58

~%

8-Quinazolinecarbonitrile,1,4-dihydro-4,6,7-trimethyl结构式

8-Quinazolineca...

73318-20-4

文献:Fatmi, Aqeel A.; Vaidya, Niteen A.; Iturrian, W. B.; Blanton, C. DeWitt Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 772 - 778

 靶点实验

查看更多实验

实验名称:Evaluated for seizure threshold test at a dose 25 mg/kg &MST is the metrazole seizure...
来源:ChEMBL
靶标:Mus musculus
External Id:CHEMBL738891
实验名称:QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源:The Scripps Research Institute Molecular Screening Center
靶标:disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id:ADAM17_INH_QFRET_1536_1X%INH PRUN
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
实验名称:qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
来源:NCGC
靶标:TDP1 protein [Homo sapiens]
External Id:TDP1100
实验名称:qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
来源:NCGC
靶标:TDP1 protein [Homo sapiens]
External Id:TDP1101
实验名称:Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Bas...
来源:Broad Institute
靶标:N/A
External Id:2134-01_Inhibitor_SinglePoint_HTS_Activity_Set2
实验名称:Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ...
来源:ChEMBL
靶标:Klebsiella pneumoniae
External Id:CHEMBL4296186
实验名称:Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
来源:Broad Institute
靶标:FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id:2147-01_Inhibitor_SinglePoint_HTS_Activity
实验名称:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
来源:Broad Institute
靶标:N/A
External Id:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
实验名称:Identifying Sarm1 TIR NADase inhibitors through high throughput HPLC assay
来源:24386
靶标:N/A
External Id:Sarm1 TIR NADase inhibitors
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 英文别名

8-Cyano-4,6,7-trimethyl-3,4-dihydroquinazoline
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