氟哌啶醇癸酸酯

• 常用名: 氟哌啶醇癸酸酯
• 英文名: 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidyl decanoate
• CAS号: 74050-97-8
• 分子量: 530.11400
• 密度: 1.14 g/cm3
• 沸点: 615.5ºC at 760 mmHg
• 分子式: C₃₁H₄₁ClFNO₃
• 熔点: 326.1ºC
• 闪点: 326.1ºC

氟哌啶醇癸酸酯用途

癸酸氟哌啶醇具有抗精神病活性。癸酸氟哌啶醇可用于精神分裂症和分裂情感障碍研究[1]。

氟哌啶醇癸酸酯名称

• 中文名: 4-(4-氯苯基)-1-[4-(4-氟苯基)-4-氧丁基]-4-哌啶癸酸盐
• 英文名: [4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] decanoate
• 中文别名: 氟哌啶醇癸酸盐

氟哌啶醇癸酸酯生物活性

• 描述: 癸酸氟哌啶醇具有抗精神病活性。癸酸氟哌啶醇可用于精神分裂症和分裂情感障碍研究[1]。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 参考文献:

  [1]. R Beresford, et al. Haloperidol decanoate. A preliminary review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in psychosis. Drugs. 1987 Jan;33(1):31-49.

氟哌啶醇癸酸酯物理化学性质

• 密度: 1.14 g/cm3
• 沸点: 615.5ºC at 760 mmHg
• 熔点: 326.1ºC
• 分子式: C₃₁H₄₁ClFNO₃
• 分子量: 530.11400
• 闪点: 326.1ºC
• 精确质量: 529.27600
• PSA: 46.61000
• LogP: 8.05510
• InChIKey: GUTXTARXLVFHDK-UHFFFAOYSA-N
• SMILES: CCCCCCCCCC(=O)OC1(c2ccc(Cl)cc2)CCN(CCCC(=O)c2ccc(F)cc2)CC1
• 折射率: 1.554
• 储存条件: -20°C
• 水溶解性: Practically insoluble in water, very soluble in ethanol (96 per cent), in methanol and in methylene chloride.

氟哌啶醇癸酸酯毒性和生态

氟哌啶醇癸酸酯安全信息

• 危险品运输编码: UN 3249
• 包装等级: III
• 危险类别: 6.1(b)

氟哌啶醇癸酸酯靶点实验

查看更多实验

实验名称：Liver toxicity in human assessed as induction of drug-induced liver injury by measuri... 来源：ChEMBL 靶标：Homo sapiens External Id：CHEMBL4029349

实验名称：Liver toxicity in human assessed as induction of drug-induced liver injury by measuri... 来源：ChEMBL 靶标：Homo sapiens External Id：CHEMBL4029350

实验名称：uHTS identification of small molecule modulators of Rev-erb Alpha. 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：SBCCG-A1016-RevErbaLBD-Primary-Assay

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VER... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4513082

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Cac... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4303805

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：Displacement of [3H]spiperone from human D2long receptor stably expressed in CHO cell... 来源：ChEMBL 靶标：D(2) dopamine receptor External Id：CHEMBL3369121

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry 来源：NCGC External Id：TRND-SARS-CoV-2-PP

实验名称：Displacement of [3H]spiperone from human D4.4 receptor stably expressed in CHO cell m... 来源：ChEMBL 靶标：D(4) dopamine receptor External Id：CHEMBL3369124

共22条，当前第1页，共3页

1

2

3

氟哌啶醇癸酸酯英文别名

• HALOPERIDOL DECANOATE
• KD 136
• Haldol decanoas
• EINECS 277-679-7
• KD 16
• UNII-AC20PJ4101