2-Amino-6-(2-hydroxyphenyl)-4-(piperidin-3-yl)nicotinonitrile

• 常用名: 2-Amino-6-(2-hydroxyphenyl)-4-(piperidin-3-yl)nicotinonitrile
• 英文名: 2-Amino-6-(2-hydroxyphenyl)-4-(piperidin-3-yl)nicotinonitrile
• CAS号: 744215-99-4
• 分子量: 294.35
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₁₈N₄O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-Amino-6-(2-hydroxyphenyl)-4-(piperidin-3-yl)nicotinonitrile

物理化学性质

• 分子式: C₁₇H₁₈N₄O
• 分子量: 294.35
• InChIKey: CDNQNPSWFHDZDZ-UHFFFAOYSA-N
• SMILES: N#Cc1c(C2CCCNC2)cc(-c2ccccc2O)nc1N

靶点实验

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实验名称：Inhibition of IKKbeta in mouse CIA model splenocytes assessed as inhibition of TNFalp... 来源：ChEMBL 靶标：Inhibitor of nuclear factor kappa-B kinase subunit beta External Id：CHEMBL2073527

实验名称：Inhibition of IKKalpha 来源：ChEMBL 靶标：Inhibitor of nuclear factor kappa-B kinase subunit alpha External Id：CHEMBL2073528

实验名称：Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta) 来源：ChEMBL 靶标：Inhibitor of nuclear factor kappa-B kinase subunit beta External Id：CHEMBL833584

实验名称：Inhibitory activity against recombinant human I-kappa-B-kinase beta 来源：ChEMBL 靶标：Inhibitor of nuclear factor kappa-B kinase subunit beta External Id：CHEMBL827106

实验名称：Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assay 来源：ChEMBL 靶标：Inhibitor of nuclear factor kappa-B kinase subunit beta External Id：CHEMBL1775258

实验名称：Inhibition of IKKbeta using 5FAM-GRHDSGLDSMK-NH2 as substrate incubated for 10 mins p... 来源：ChEMBL 靶标：Inhibitor of nuclear factor kappa-B kinase subunit beta External Id：CHEMBL2073525

实验名称：Inhibition of IKKbeta in human HeLa cells assessed as inhibition of TPA-induced NFkap... 来源：ChEMBL 靶标：Inhibitor of nuclear factor kappa-B kinase subunit beta External Id：CHEMBL2073526

实验名称：Inhibition of IKK2 at 10 uM using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assay 来源：ChEMBL 靶标：Inhibitor of nuclear factor kappa-B kinase subunit beta External Id：CHEMBL1775257

实验名称：Inhibition of IKKbeta using 5FAM-GRHDSGLDSMK-NH2 as substrate at 10 uM incubated for ... 来源：ChEMBL 靶标：Inhibitor of nuclear factor kappa-B kinase subunit beta External Id：CHEMBL2073535

实验名称：Inhibition of human IKKbeta using GST-IkappaBalpha as substrate 来源：ChEMBL 靶标：Inhibitor of nuclear factor kappa-B kinase subunit beta External Id：CHEMBL2378059

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