4-[2-[2-环戊基-5-[(5,7-二甲基[1,2,4]噻唑并[1,5-a]嘧啶)甲基]-3,6-二氢-4-羟基-6-氧代-2H-吡喃]乙基]-2-氟-α,α-二甲基苯乙腈

• 常用名: 4-[2-[2-环戊基-5-[(5,7-二甲基[1,2,4]噻唑并[1,5-a]嘧啶)甲基]-3,6-二氢-4-羟基-6-氧代-2H-吡喃]乙基]-2-氟-α,α-二甲基苯乙腈
• 英文名: 2-[4-(2-{2-cyclopentyl-5-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-6-oxo-3,6-dihydro-2H-pyran-2-yl}ethyl)-2-fluorophenyl]-2-methylpropanenitrile
• CAS号: 749929-33-7
• 分子量: 531.62100
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₀H₃₄FN₅O₃
• 熔点: N/A
• 闪点: N/A

名称

• 中文名: 4-[2-[2-环戊基-5-[(5,7-二甲基[1,2,4]噻唑并[1,5-a]嘧啶)甲基]-3,6-二氢-4-羟基-6-氧代-2H-吡喃]乙基]-2-氟-α,α-二甲基苯乙腈
• 英文名: 2-[4-(2-{2-cyclopentyl-5-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-6-oxo-3,6-dihydro-2H-pyran-2-yl}ethyl)-2-fluorophenyl]-2-methylpropanenitrile

物理化学性质

• 分子式: C₃₀H₃₄FN₅O₃
• 分子量: 531.62100
• 精确质量: 531.26500
• PSA: 113.40000
• LogP: 5.54468
• InChIKey: XPRDGKCNHYYXEJ-UHFFFAOYSA-N
• SMILES: Cc1cc(C)n2nc(CC3=C(O)CC(CCc4ccc(C(C)(C)C#N)c(F)c4)(C4CCCC4)OC3=O)nc2n1

靶点实验

查看更多实验

实验名称：Inhibition of Hepatitis C virus NS5B polymerase 来源：ChEMBL 靶标：RNA-directed RNA polymerase External Id：CHEMBL5348065

实验名称：Bioavailability in rat at 10 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL894277

实验名称：Total plasma clearance in rat at 25 mg/kg, po or 5 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL894271

实验名称：Volume of distribution in rat at 25 mg/kg, po or 5 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL894272

实验名称：Antiviral activity against HCV assessed as reduction in viral growth 来源：ChEMBL 靶标：Hepacivirus hominis External Id：CHEMBL5348071

实验名称：Half life in rat at 25 mg/kg, po or 5 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL894273

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英文别名

• 2-(4-(2-((1,1'-Biphenyl)-4-yl)vinyl)phenyl)-5,7-dimethylbenzoxazole
• 2-[4-(2-biphenyl-4-yl-vinyl)-phenyl]-5,7-dimethyl-benzooxazole
• Benzoxazole,2-(4-(2-((1,1'-biphenyl)-4-yl)ethenyl)phenyl)-5,7-dimethyl
• 4-phenyl-4'-(5",7"-di-methylbenzoxazol-2"-yl)-stilbene
• 2-(4-{2-[2-cyclopentyl-5-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylmethyl)-4-hydroxy-6-oxo-3,6-dihydro-2H-pyran-2-yl]-ethyl}-2-fluoro-phenyl)-2-methyl-propionitrile