1,4-二氢-2,6-二甲基-4-(3-硝基苯基)-3,5-吡啶二甲酸 3-(2-氰基乙基) 5-甲基酯

• 常用名: 1,4-二氢-2,6-二甲基-4-(3-硝基苯基)-3,5-吡啶二甲酸 3-(2-氰基乙基) 5-甲基酯
• 英文名: 2,6-dimethyl-4-(3-nitrophenyl)-5-methoxycarbonyl-1,4-dihydropyridine-3-carboxylic acid 2-cyanoethyl ester
• CAS号: 75130-24-4
• 分子量: 385.37100
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₁₉N₃O₆
• 熔点: 128-131ºC
• 闪点: N/A

名称

• 中文名: 1,4-二氢-2,6-二甲基-4-(3-硝基苯基)-3,5-吡啶二甲酸 3-(2-氰基乙基) 5-甲基酯
• 英文名: 5-O-(2-cyanoethyl) 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

物理化学性质

• 熔点: 128-131ºC
• 分子式: C₁₉H₁₉N₃O₆
• 分子量: 385.37100
• 精确质量: 385.12700
• PSA: 134.24000
• LogP: 3.31148
• InChIKey: PVYKGJCGTZQNJL-UHFFFAOYSA-N
• SMILES: COC(=O)C1=C(C)NC(C)=C(C(=O)OCCC#N)C1c1cccc([N+](=O)[O-])c1

靶点实验

查看更多实验

实验名称：Selectivity ratio of IC50 for rabbit Cav1.2 to IC50 for rat Cav1.3 来源：ChEMBL 靶标：N/A External Id：CHEMBL1121086

实验名称：Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition... 来源：ChEMBL 靶标：Voltage-dependent L-type calcium channel subunit alpha-1C External Id：CHEMBL1121085

实验名称：Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of... 来源：ChEMBL 靶标：Voltage-dependent L-type calcium channel subunit alpha-1D External Id：CHEMBL1121084

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英文别名

• 2,6-dimethyl-4-(3-nitrophenyl)-5-methoxycarbonyl-1,4-dihydropyridine-3-carboxylic acid 2-cyanoethyl ester
• 2-Cyanoethyl phosphate
• 3-(phosphonatooxy)propanenitrile
• cyanoethyl phosphate
• 3-(2-cyanoethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• 2,6-dimethyl-3-carbomethoxy-4-(3-nitrophenyl)-5-(2-cyano)ethoxycarbonyl-1,4-dihydropyridine
• Propanenitrile,3-(phosphonooxy)
• 2-cyanoethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
• 2-cyanoethyl dihydrogenphosphate
• 1,4-Dihydro-2,6-Dimethyl-4-(3-Nitrophenyl)-3,5-Pyridinedicarboxylic Acid 3-(2-Cyanoethyl) 5-Methyl Ester
• Lercanidipine Impurity 2