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2-[(5-iodo-2,4-dioxopyrimidin-1-yl)methoxy]ethyl acetate

更新时间:2026-01-30 19:54:21

2-[(5-iodo-2,4-dioxopyrimidin-1-yl)methoxy]ethyl acetate结构式
2-[(5-iodo-2,4-dioxopyrimidin-1-yl)methoxy]ethyl acetate结构式
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常用名 2-[(5-iodo-2,4-dioxopyrimidin-1-yl)methoxy]ethyl acetate 英文名 2-[(5-iodo-2,4-dioxopyrimidin-1-yl)methoxy]ethyl acetate
CAS号 78097-08-2 分子量 354.09900
密度 N/A 沸点 N/A
分子式 C9H11IN2O5 熔点 N/A
MSDS N/A 闪点 N/A

 名称

英文名 2-[(5-iodo-2,4-dioxopyrimidin-1-yl)methoxy]ethyl acetate
英文别名 更多

 物理化学性质

分子式 C9H11IN2O5
分子量 354.09900
精确质量 353.97100
PSA 90.65000
LogP 0.09070
InChIKey PQMMBDHYPCKLIQ-UHFFFAOYSA-N
SMILES CC(=O)OCCOCn1cc(I)c(=O)[nH]c1=O

 合成线路

~78%

2-[(5-iodo-2,4-dioxopyrimidin-1-yl)methoxy]ethyl acetate结构式

2-[(5-iodo-2,4-...

78097-08-2

文献:Amblard, Franck; Aucagne, Vincent; Guenot, Pierre; Schinazi, Raymond F.; Agrofoglio, Luigi A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 4 p. 1239 - 1248

~%

2-[(5-iodo-2,4-dioxopyrimidin-1-yl)methoxy]ethyl acetate结构式

2-[(5-iodo-2,4-...

78097-08-2

文献:Kelley, James L.; Kelsey, John E.; Hall, William R.; Krochmal, Mark P.; Schaeffer, Howard J. Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 753 - 756

~%

2-[(5-iodo-2,4-dioxopyrimidin-1-yl)methoxy]ethyl acetate结构式

2-[(5-iodo-2,4-...

78097-08-2

文献:Kelley, James L.; Kelsey, John E.; Hall, William R.; Krochmal, Mark P.; Schaeffer, Howard J. Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 753 - 756

~62%

2-[(5-iodo-2,4-dioxopyrimidin-1-yl)methoxy]ethyl acetate结构式

2-[(5-iodo-2,4-...

78097-08-2

文献:Colla; Busson; De Clercq; Vanderhaeghe European Journal of Medicinal Chemistry, 1982 , vol. 17, # 6 p. 569 - 576

~32%

2-[(5-iodo-2,4-dioxopyrimidin-1-yl)methoxy]ethyl acetate结构式

2-[(5-iodo-2,4-...

78097-08-2

文献:Kelley, James L.; Kelsey, John E.; Hall, William R.; Krochmal, Mark P.; Schaeffer, Howard J. Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 753 - 756

~%

2-[(5-iodo-2,4-dioxopyrimidin-1-yl)methoxy]ethyl acetate结构式

2-[(5-iodo-2,4-...

78097-08-2

文献:Rosowsky; Kim; Wick Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1177 - 1181

~%

2-[(5-iodo-2,4-dioxopyrimidin-1-yl)methoxy]ethyl acetate结构式

2-[(5-iodo-2,4-...

78097-08-2

文献:Robins; Hatfield Canadian Journal of Chemistry, 1982 , vol. 60, # 5 p. 547 - 553

 靶点实验

查看更多实验

实验名称:Cytotoxicity against mouse L cells in cell culture; No significant cytotoxicity was o...
来源:ChEMBL
靶标:L cells
External Id:CHEMBL701374
实验名称:Plaque-inhibition against Herpes simplex virus type 1 (HSV-1) in cell culture at 50 u...
来源:ChEMBL
靶标:Human alphaherpesvirus 1
External Id:CHEMBL696162
实验名称:Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标:HCMV UL50
External Id:HMS1262
实验名称:Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标:ORF 73 [Human herpesvirus 8 type M]
External Id:HMS791
实验名称:High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id:HMS1303
实验名称:A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id:HMS979
实验名称:Cell-based high throughput primary assay to identify activators of GPR151
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id:GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
实验名称:AlphaScreen-based biochemical high throughput primary assay to identify activators of...
来源:The Scripps Research Institute Molecular Screening Center
靶标:N/A
External Id:FBW7_ACT_ALPHA_1536_1X%ACT PRUN
实验名称:AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
来源:The Scripps Research Institute Molecular Screening Center
External Id:MITF_INH_Alpha_1536_1X%INH PRUN
实验名称:Cytotoxicity against Detroit 98 cells in cell culture; No significant cytotoxicity wa...
来源:ChEMBL
靶标:Detroit 98
External Id:CHEMBL880685
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 英文别名

hms1617n15
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