N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(pyridin-2-ylmethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide

• 常用名: N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(pyridin-2-ylmethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
• 英文名: N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(pyridin-2-ylmethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
• CAS号: 781649-10-3
• 分子量: 575.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₀H₃₁F₂N₇O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(pyridin-2-ylmethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide

物理化学性质

• 分子式: C₃₀H₃₁F₂N₇O₃
• 分子量: 575.6
• InChIKey: RJDQCXSYOMEUKI-NTKDMRAZSA-N
• SMILES: O=C(NC1CCC(c2cccc(F)c2F)CN(Cc2ccccn2)C1=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1

靶点实验

查看更多实验

实验名称：Displacement of [125I]CGPR from human CL receptor expressed in HEK293 cells 来源：ChEMBL 靶标：Calcitonin gene-related peptide type 1 receptor External Id：CHEMBL899870

实验名称：Oral bioavailability in dog at 1 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL899875

实验名称：Antagonist activity at human CL receptor expressed in E10 cells assessed as CGRP-stim... 来源：ChEMBL 靶标：Calcitonin gene-related peptide type 1 receptor External Id：CHEMBL899871

实验名称：Antagonist activity at human CL receptor expressed in E10 cells assessed as CGRP-stim... 来源：ChEMBL 靶标：Calcitonin gene-related peptide type 1 receptor External Id：CHEMBL899872

实验名称：Ratio of IC50 for human CL receptor in E10 cells over IC50 human CL receptor in E10 c... 来源：ChEMBL 靶标：Calcitonin gene-related peptide type 1 receptor External Id：CHEMBL899873

实验名称：Oral bioavailability in rat at 10 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL899874

共6条，当前第1页，共1页

1