2-Piperidineacetamide, N-[(1R)-6-[[(1,1-dimethylethyl)amino]methyl]-1,2,3,4-tetrahydro-1-naphthalenyl]-1-[[3-(trifluoromethyl)phenyl]sulfonyl]-, (2S)

• 常用名: 2-Piperidineacetamide, N-[(1R)-6-[[(1,1-dimethylethyl)amino]methyl]-1,2,3,4-tetrahydro-1-naphthalenyl]-1-[[3-(trifluoromethyl)phenyl]sulfonyl]-, (2S)
• 英文名: 2-Piperidineacetamide, N-[(1R)-6-[[(1,1-dimethylethyl)amino]methyl]-1,2,3,4-tetrahydro-1-naphthalenyl]-1-[[3-(trifluoromethyl)phenyl]sulfonyl]-, (2S)
• CAS号: 783239-41-8
• 分子量: 565.7
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₉H₃₈F₃N₃O₃S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-Piperidineacetamide, N-[(1R)-6-[[(1,1-dimethylethyl)amino]methyl]-1,2,3,4-tetrahydro-1-naphthalenyl]-1-[[3-(trifluoromethyl)phenyl]sulfonyl]-, (2S)

物理化学性质

• 分子式: C₂₉H₃₈F₃N₃O₃S
• 分子量: 565.7
• InChIKey: BFWDXOBUPPVYOP-UHFFFAOYSA-N
• SMILES: CC(C)(C)NCc1ccc2c(c1)CCCC2NC(=O)CC1CCCCN1S(=O)(=O)c1cccc(C(F)(F)F)c1

靶点实验

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实验名称：Antagonist activity at human bradykinin B1 receptor expressed in CHO cells assessed a... 来源：ChEMBL 靶标：B1 bradykinin receptor External Id：CHEMBL1780462

实验名称：Metabolic stability in human liver microsomes assessed as compound degradation 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL1780465

实验名称：Antagonist activity at human bradykinin B1 receptor 来源：ChEMBL 靶标：B1 bradykinin receptor External Id：CHEMBL1780464

实验名称：Clearance in rat at 1 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL868442

实验名称：Volume of distribution in rat at 1 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL868443

实验名称：Oral bioavailability in rat at 10 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL868444

实验名称：Inhibition of human B1 receptor 来源：ChEMBL 靶标：B1 bradykinin receptor External Id：CHEMBL866612

实验名称：Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cell... 来源：ChEMBL 靶标：B1 bradykinin receptor External Id：CHEMBL1005610

实验名称：Inhibition of human B1 receptor by calcium influx functional assay 来源：ChEMBL 靶标：B1 bradykinin receptor External Id：CHEMBL868440

实验名称：Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequori... 来源：ChEMBL 靶标：B1 bradykinin receptor External Id：CHEMBL1005609

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