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Abarelix acetate

更新时间:2024-01-19 11:15:08

Abarelix acetate结构式
Abarelix acetate结构式
品牌特惠专场
常用名 Abarelix acetate 英文名 Abarelix acetate
CAS号 785804-17-3 分子量 1476.115
密度 N/A 沸点 N/A
分子式 C74H99ClN14O16 熔点 N/A
MSDS N/A 闪点 N/A

 Abarelix acetate用途


Abarelix acetate is a synthetic third generation gonadotropin-releasing hormone receptor (GnRHR) antagonist. It increases histamine release from rat peritoneal mast cells in vitro and from a human skin model ex vivo. In vivo, abarelix decreases plasma luteinizing hormone (LH) levels six hours post-treatment in castrated rats, with levels returning to baseline within 24 hours.3 Abarelix (2 mg/kg) also transiently decreases plasma testosterone levels in intact rats, with levels returning to baseline within seven days post-treatment. Formulations containing abarelix have previously been used in the treatment of advanced prostate cancer.

 Abarelix acetate名称

英文名 Abarelix (acetate)
英文别名 更多

 Abarelix acetate物理化学性质

分子式 C74H99ClN14O16
分子量 1476.115
精确质量 1474.705200

 Abarelix acetate英文别名

Abarelix (acetate)
D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-N-methyl-L-tyrosyl-D-asparaginyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-, acetate ( 1:1)
MFCD17011970
N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-N-methyl-L-tyrosyl-D-asparaginyl-L-leucyl-N6-isopropyl-L-lysyl-L-prolyl-D-alaninamide acetate (1:1)
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