2-{4-[(6,7-Dimethoxyquinazolin-4-yl)amino]-1h-pyrazol-1-yl}-n-(3-fluorophenyl)acetamide

• 常用名: 2-{4-[(6,7-Dimethoxyquinazolin-4-yl)amino]-1h-pyrazol-1-yl}-n-(3-fluorophenyl)acetamide
• 英文名: 2-{4-[(6,7-Dimethoxyquinazolin-4-yl)amino]-1h-pyrazol-1-yl}-n-(3-fluorophenyl)acetamide
• CAS号: 786682-88-0
• 分子量: 422.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₁₉FN₆O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-{4-[(6,7-Dimethoxyquinazolin-4-yl)amino]-1h-pyrazol-1-yl}-n-(3-fluorophenyl)acetamide

物理化学性质

• 分子式: C₂₁H₁₉FN₆O₃
• 分子量: 422.4
• InChIKey: NGBFROQDGZCMCE-UHFFFAOYSA-N
• SMILES: COc1cc2ncnc(Nc3cnn(CC(=O)Nc4cccc(F)c4)c3)c2cc1OC

靶点实验

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实验名称：Oral bioavailability in rat 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1942926

实验名称：Inhibition of PDGFRbeta phosphorylation by cell based assay 来源：ChEMBL 靶标：Platelet-derived growth factor receptor beta External Id：CHEMBL1942929

实验名称：Chemical stability of the compound at pH 1 来源：ChEMBL 靶标：N/A External Id：CHEMBL1942928

实验名称：Inhibition of CSF1R phosphorylation by cell based assay 来源：ChEMBL 靶标：Macrophage colony-stimulating factor 1 receptor External Id：CHEMBL1942931

实验名称：Inhibition of VEGFR3 phosphorylation by cell based assay 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 3 External Id：CHEMBL1942930

实验名称：Inhibition of FLT3 phosphorylation by cell based assay 来源：ChEMBL 靶标：Receptor-type tyrosine-protein kinase FLT3 External Id：CHEMBL1942933

实验名称：ASTRAZENECA: Solubility in pH7.4 buffer using solid starting material using the metho... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301364

实验名称：Inhibition of PDGFRalpha phosphorylation by cell based assay 来源：ChEMBL 靶标：Platelet-derived growth factor receptor alpha External Id：CHEMBL1943691

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