3-[癸基二甲基甲硅烷基] -N- [2-(4-甲基苯基)-1-苯乙基]丙酰胺

更新时间：2025-08-27 17:28:00

3-[癸基二甲基甲硅烷基] -N- [2-(4-甲基苯基)-1-苯乙基]丙酰胺结构式	常用名	3-[癸基二甲基甲硅烷基] -N- [2-(4-甲基苯基)-1-苯乙基]丙酰胺	英文名	Sandoz 58-035
	CAS号	78934-83-5	分子量	465.78600
	密度	0.952g/cm3	沸点	584.4ºC at 760 mmHg
	分子式	C₃₀H₄₇NOSi	熔点	N/A
	MSDS	中文版美版	闪点	307.2ºC

用途

Sandoz 58-035 用于诱导小鼠腹腔巨噬细胞中未折叠蛋白反应（UPR）和模式识别受体（PRR）的同时激活。

中文名	3-[癸基二甲基甲硅烷基] -N- [2-(4-甲基苯基)-1-苯乙基]丙酰胺
英文名	3-[decyl(dimethyl)silyl]-N-[2-(4-methylphenyl)-1-phenylethyl]propanamide
英文别名	更多

密度	0.952g/cm3
沸点	584.4ºC at 760 mmHg
分子式	C₃₀H₄₇NOSi
分子量	465.78600
闪点	307.2ºC
精确质量	465.34300
PSA	32.59000
LogP	9.47450
InChIKey	NBYATBIMYLFITE-UHFFFAOYSA-N
SMILES	CCCCCCCCCC[Si](C)(C)CCC(=O)NC(Cc1ccc(C)cc1)c1ccccc1
外观性状	固体
折射率	1.512
储存条件	2-8°C

MSDS英文版

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码	NONH for all modes of transport
WGK德国	3

An LXR-NCOA5 gene regulatory complex directs inflammatory crosstalk-dependent repression of macrophage cholesterol efflux.

EMBO J. 34 , 1244-58, (2015)

LXR-cofactor complexes activate the gene expression program responsible for cholesterol efflux in macrophages. Inflammation antagonizes this program, resulting in foam cell formation and atheroscleros...

Neutrophil extracellular trap-derived enzymes oxidize high-density lipoprotein: an additional proatherogenic mechanism in systemic lupus erythematosus.

Arthritis Rheumatology 66(9) , 2532-44, (2014)

Oxidative stress and oxidized high-density lipoprotein (HDL) are implicated as risk factors for cardiovascular disease (CVD) in systemic lupus erythematosus (SLE). Yet, how HDL is oxidized and rendere...

Lipid droplet changes in proliferating and quiescent 3T3 fibroblasts.

Histochem. Cell Biol. 129(5) , 611-21, (2008)

Lipid droplets (LDs) are fat-storing organelles present in virtually all eukaryotic cells and involved in many aspects of cell biology related to lipid metabolism and cholesterol homeostasis. In this ...

实验名称：qHTS to identify inhibitors of the New Delhi Metallo-beta-lactamase (NDM): assay vali...
来源：NCGC
External Id：adst_MBL_Abs_LOPAC_o1

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
来源：NCGC
靶标：N/A
External Id：SERCaMPGLuc-p1-antagonist

实验名称：qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2
来源：NCGC
靶标：eyes absent homolog 2 isoform a [Homo sapiens]
External Id：EYA2477

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来源：ChEMBL
靶标：N/A
External Id：CHEMBL1266185

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来源：NCGC
External Id：SNCA-p-activity-luciferase

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来源：NCGC
靶标：ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens]
External Id：UBCH001

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来源：ChEMBL
靶标：Sterol O-acyltransferase 1
External Id：CHEMBL1115604

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来源：NCGC
靶标：N/A
External Id：ZIK159

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来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标：N/A
External Id：HMS1315

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来源：NCGC
靶标：N/A
External Id：ZIK097

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