4'-ACETAMIDOPHENYL 4-GUANIDINOBENZOATE HYDROCHLORIDE结构式
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常用名 | 4'-ACETAMIDOPHENYL 4-GUANIDINOBENZOATE HYDROCHLORIDE | 英文名 | 4'-ACETAMIDOPHENYL 4-GUANIDINOBENZOATE HYDROCHLORIDE |
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| CAS号 | 79119-49-6 | 分子量 | 348.78400 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C16H17ClN4O3 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
| 英文名 | 4-((Aminoiminomethyl)amino)benzoic acid 4-(acetylamino)phenyl ester hydrochloride |
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| 英文别名 | 更多 |
| 分子式 | C16H17ClN4O3 |
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| 分子量 | 348.78400 |
| 精确质量 | 348.09900 |
| PSA | 117.30000 |
| LogP | 3.91760 |
| InChIKey | CBYYAOPEHXAUHL-UHFFFAOYSA-N |
| SMILES | CC(=O)Nc1ccc(OC(=O)c2ccc(N=C(N)N)cc2)cc1.Cl |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| 危险品运输编码 | NONH for all modes of transport |
| RTECS号 | DG2800520 |
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Inhibition of a tumour protease with 3,4-dichloroisocoumarin, pentamidine-isethionate and guanidino derivatives.
J. Enzym. Inhib. 8(3) , 213-21, (1994) Guanidinobenzoatase (GB) is a cell surface proteolytic enzyme capable of degrading fibronectin, and is associated with tumour cells and cells capable of migration. The location of active GB in section... |
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Synthesis and inhibition of human acrosin and trypsin and acute toxicity of aryl 4-guanidinobenzoates.
J. Med. Chem. 29 , 514, (1986) The aryl 4-guanidinobenzoate, 4'-nitrophenyl 4-guanidinobenzoate (NPGB), is a potent inhibitor of sperm acrosin, an enzyme with an essential function in the fertilization process. NPGB prevents fertil... |
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Trypsin inhibitors prevent the progesterone-initiated increase in intracellular calcium required for the human sperm acrosome reaction.
J. Exp. Zool. 258(3) , 384-93, (1991) Inhibitors of trypsin-like enzymes, benzamidine hydrochloride and 4'-acetamidophenyl 4-guanidinobenzoate (also an inhibitor of other serine proteases), were tested for their effects on the acrosome re... |
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实验名称:Lethal dose that produces death in 50% of mice within 24 hr after acute treatment
来源:ChEMBL
靶标:Mus musculus
External Id:CHEMBL727619
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| 4'-Acetamidophenyl 4-guanidinobenzoate hydrochloride |
| 4'-ACETAMIDOPHENYL-4-GUANIDINOBENZOATE HYDROCHLORIDE |