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4'-ACETAMIDOPHENYL 4-GUANIDINOBENZOATE HYDROCHLORIDE

更新时间:2025-08-31 19:57:03

4'-ACETAMIDOPHENYL 4-GUANIDINOBENZOATE HYDROCHLORIDE结构式
4'-ACETAMIDOPHENYL 4-GUANIDINOBENZOATE HYDROCHLORIDE结构式
委托求购
常用名 4'-ACETAMIDOPHENYL 4-GUANIDINOBENZOATE HYDROCHLORIDE 英文名 4'-ACETAMIDOPHENYL 4-GUANIDINOBENZOATE HYDROCHLORIDE
CAS号 79119-49-6 分子量 348.78400
密度 N/A 沸点 N/A
分子式 C16H17ClN4O3 熔点 N/A
MSDS 美版 闪点 N/A

 名称

英文名 4-((Aminoiminomethyl)amino)benzoic acid 4-(acetylamino)phenyl ester hydrochloride
英文别名 更多

 物理化学性质

分子式 C16H17ClN4O3
分子量 348.78400
精确质量 348.09900
PSA 117.30000
LogP 3.91760
InChIKey CBYYAOPEHXAUHL-UHFFFAOYSA-N
SMILES CC(=O)Nc1ccc(OC(=O)c2ccc(N=C(N)N)cc2)cc1.Cl

 安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码 NONH for all modes of transport
RTECS号 DG2800520

 文献7

更多文献
Inhibition of a tumour protease with 3,4-dichloroisocoumarin, pentamidine-isethionate and guanidino derivatives.

J. Enzym. Inhib. 8(3) , 213-21, (1994)

Guanidinobenzoatase (GB) is a cell surface proteolytic enzyme capable of degrading fibronectin, and is associated with tumour cells and cells capable of migration. The location of active GB in section...

Synthesis and inhibition of human acrosin and trypsin and acute toxicity of aryl 4-guanidinobenzoates.

J. Med. Chem. 29 , 514, (1986)

The aryl 4-guanidinobenzoate, 4'-nitrophenyl 4-guanidinobenzoate (NPGB), is a potent inhibitor of sperm acrosin, an enzyme with an essential function in the fertilization process. NPGB prevents fertil...

Trypsin inhibitors prevent the progesterone-initiated increase in intracellular calcium required for the human sperm acrosome reaction.

J. Exp. Zool. 258(3) , 384-93, (1991)

Inhibitors of trypsin-like enzymes, benzamidine hydrochloride and 4'-acetamidophenyl 4-guanidinobenzoate (also an inhibitor of other serine proteases), were tested for their effects on the acrosome re...

 靶点实验

查看更多实验

实验名称:Lethal dose that produces death in 50% of mice within 24 hr after acute treatment
来源:ChEMBL
靶标:Mus musculus
External Id:CHEMBL727619
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 英文别名

4'-Acetamidophenyl 4-guanidinobenzoate hydrochloride
4'-ACETAMIDOPHENYL-4-GUANIDINOBENZOATE HYDROCHLORIDE
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