Dynorphin A (1-13) amide trifluoroacetate salt

• 常用名: Dynorphin A (1-13) amide trifluoroacetate salt
• 英文名: Dynorphin A (1-13) amide trifluoroacetate salt
• CAS号: 79515-34-7
• 分子量: 1602.970
• 密度: 1.4±0.1 g/cm3
• 沸点: N/A
• 分子式: C₇₅H₁₂₇N₂₅O₁₄
• 熔点: N/A
• 闪点: N/A

用途

Dynorphin A (1-13) amide 是一种内源性阿片肽,对吗啡诱导的镇痛具有拮抗作用。

名称

• 英文名: Dynorphin A (1-13) amide trifluoroacetate salt

生物活性

• 描述: Dynorphin A (1-13) amide 是一种内源性阿片肽,对吗啡诱导的镇痛具有拮抗作用。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Woo S,et al. Dynorphin(1-10)amide: a potent and selective analog of dynorphin(1-13). Life Sci. 1982 Oct 18-25;31(16-17):1817-20.

物理化学性质

• 密度: 1.4±0.1 g/cm3
• 分子式: C₇₅H₁₂₇N₂₅O₁₄
• 分子量: 1602.970
• 精确质量: 1601.999390
• LogP: -1.61
• 折射率: 1.648

靶点实验

查看更多实验

实验名称：Binding affinity towards Opioid receptor mu 1 expressed in CHO cells was determined b... 来源：ChEMBL 靶标：Mu-type opioid receptor External Id：CHEMBL756660

实验名称：Inhibition of [3H]- bremazocine to opioid receptor kappa of guinea pig cerebral membr... 来源：ChEMBL 靶标：Kappa-type opioid receptor External Id：CHEMBL750840

实验名称：Binding affinity against Opioid receptor kappa 1 in guinea pig brain homogenate using... 来源：ChEMBL 靶标：Kappa-type opioid receptor External Id：CHEMBL756067

实验名称：Compound was tested for binding affinity towards mu-opioid receptor in rat forebrain ... 来源：ChEMBL 靶标：Mu-type opioid receptor External Id：CHEMBL844217

实验名称：Opioid receptor selectivity and expressed as ratio (kappa/mu/delta); 1/18/83 来源：ChEMBL 靶标：Kappa-type opioid receptor External Id：CHEMBL750848

实验名称：Opioid receptor activity in guinea pig ileum 来源：ChEMBL 靶标：Opioid receptor (mu and kappa) External Id：CHEMBL683697

实验名称：Potency was evaluated in guinea pig ileum relative to Dynorphin A. 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL881804

实验名称：Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells... 来源：ChEMBL 靶标：Kappa-type opioid receptor External Id：CHEMBL5253113

实验名称：Stability of the compound in simulated gastric fluid at pH 1.2 assessed as drug degra... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5033297

实验名称：Binding affinity towards opioid receptor delta 1 expressed in CHO cells was determine... 来源：ChEMBL 靶标：Delta-type opioid receptor External Id：CHEMBL757535

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英文别名

• L-Tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N5-(diaminomethylene)-L-ornithyl-N5-(diaminomethylene)-L-ornithyl-L-isoleucyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-L-lysyl-L-leucyl-L-lysinamid 
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