DNA拓扑异构酶I
DNA拓扑异构酶I结构式
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常用名 | DNA拓扑异构酶I | 英文名 | TOPOISOMERASE I |
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| CAS号 | 80449-01-0 | 分子量 | N/A | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | N/A | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
| 中文名 | DNA拓扑异构酶I |
|---|---|
| 英文名 | TOPOISOMERASE I |
| 外观性状 | buffered aqueous glycerol solution |
|---|---|
| 储存条件 | −70°C |
| 个人防护装备 | Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US) |
|---|---|
| 危险品运输编码 | NONH for all modes of transport |
| WGK德国 | 3 |
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Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures.
Nat. Struct. Mol. Biol. 20(3) , 387-95, (2013) DNA supercoiling is an inherent consequence of twisting DNA and is critical for regulating gene expression and DNA replication. However, DNA supercoiling at a genomic scale in human cells is uncharact... |
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A rapid and sensitive assay for DNA-protein covalent complexes in living cells.
Nucleic Acids Res. 41(9) , e104, (2013) A number of proteins form covalent bonds with DNA as obligatory transient intermediates in normal nuclear transactions. Drugs that trap these complexes have proven to be potent therapeutics in both ca... |
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New insights into DNA-binding by type IIA topoisomerases.
Curr. Opin. Struct. Biol. 23(1) , 125-33, (2013) Type IIA topoisomerases catalyze the passage of two DNA duplexes across each other to resolve the entanglements and coiling of cellular DNA. The ability of these enzymes to interact simultaneously but... |
