(20R)-人参皂苷Rh1

• 常用名: (20R)-人参皂苷Rh1
• 英文名: (20R)-Ginsenoside Rh1
• CAS号: 80952-71-2
• 分子量: 638.872
• 密度: 1.23±0.1 g/cm3
• 沸点: 755.1±60.0 °C at 760 mmHg
• 分子式: C₃₆H₆₂O₉
• 熔点: N/A
• 闪点: 410.5±32.9 °C

(20R)-人参皂苷Rh1用途

(20R)-Ginsenoside Rh1 是Ginsenoside Rh1 的 R 型异构体,可从Panax Ginseng 中分离得到,可抑制凝血酶诱导的纤维蛋白原向纤维蛋白的转化。

(20R)-人参皂苷Rh1名称

• 中文名: (20R)-人参皂苷 Rh1
• 英文名: (2R,3R,4S,5S,6R)-2-[[(6R,8R,10R,12S,14S)-3,12-dihydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

(20R)-人参皂苷Rh1生物活性

• 描述: (20R)-Ginsenoside Rh1 是Ginsenoside Rh1 的 R 型异构体,可从Panax Ginseng 中分离得到,可抑制凝血酶诱导的纤维蛋白原向纤维蛋白的转化。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Fan X, et al. Pharmacokinetic Comparison of 20(R)- and 20(S)-Ginsenoside Rh1 and 20(R)- and 20(S)-Ginsenoside Rg3 in Rat Plasma following Oral Administration of Radix Ginseng Rubra and Sheng-Mai-San Extracts. Evid Based Complement Alternat Med. 2017;2017:6451963.

(20R)-人参皂苷Rh1物理化学性质

• 密度: 1.23±0.1 g/cm3
• 沸点: 755.1±60.0 °C at 760 mmHg
• 分子式: C₃₆H₆₂O₉
• 分子量: 638.872
• 闪点: 410.5±32.9 °C
• 精确质量: 638.439392
• PSA: 160.07000
• LogP: 3.74
• InChIKey: RAQNTCRNSXYLAH-PQYWRUIPSA-N
• SMILES: CC(C)=CCCC(C)(O)C1CCC2(C)C1C(O)CC1C3(C)CCC(O)C(C)(C)C3C(OC3OC(CO)C(O)C(O)C3O)CC12C
• 蒸汽压: 0.0±5.7 mmHg at 25°C
• 折射率: 1.581
• 水溶解性: Insuluble (2.2E-3 g/L) (25 ºC)

(20R)-人参皂苷Rh1靶点实验

查看更多实验

实验名称：Cytotoxicity against human SW480 cells 来源：ChEMBL 靶标：SW480 External Id：CHEMBL3595529

实验名称：Cytotoxicity against human HL60 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL3635509

实验名称：Neurotrophic activity in rat PC12 cells assessed as stimulation of NGF-induced neurit... 来源：ChEMBL 靶标：PC-12 External Id：CHEMBL3595458

实验名称：Cytotoxicity against human A549 cells 来源：ChEMBL 靶标：A549 External Id：CHEMBL3595527

实验名称：Cytotoxicity against human MCF7 cells 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL3595528

实验名称：Activation of SIRT1 (unknown origin) after 45 mins by NAD/NADH enzyme-based fluoromet... 来源：ChEMBL 靶标：NAD-dependent protein deacetylase sirtuin-1 External Id：CHEMBL3635511

实验名称：Cytotoxicity against human HL60 cells 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL3595525

实验名称：Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL3635510

实验名称：Cytotoxicity against human SMMC-7712 cells 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3595526

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(20R)-人参皂苷Rh1英文别名

• (3β,6α,12β,20R)-3,12,20-Trihydroxydammar-24-en-6-yl β-D-glucopyranoside
• β-D-Glucopyranoside, (3β,6α,12β,20R)-3,12,20-trihydroxydammar-24-en-6-yl
• 20(R)-Ginsenoside Rh1