ISX-9

• 常用名: ISX-9
• 英文名: Isoxazole 9 (ISX-9)
• CAS号: 832115-62-5
• 分子量: 234.274
• 密度: 1.4±0.1 g/cm3
• 沸点: 468.1±35.0 °C at 760 mmHg
• 分子式: C₁₁H₁₀N₂O₂S
• 熔点: N/A
• 闪点: 236.9±25.9 °C

ISX-9用途

ISX-9是一种成人神经干细胞分化的小分子诱导剂。

ISX-9名称

• 中文名: ISX-9
• 英文名: N-Cyclopropyl-5-(2-thienyl)-1,2-oxazole-3-carboxamide

ISX-9生物活性

• 描述: ISX-9是一种成人神经干细胞分化的小分子诱导剂。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Petrik D, et al. Functional and mechanistic exploration of an adult neurogenesis-promoting small molecule. FASEB J. 2012 Aug;26(8):3148-3162.

ISX-9物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 468.1±35.0 °C at 760 mmHg
• 分子式: C₁₁H₁₀N₂O₂S
• 分子量: 234.274
• 闪点: 236.9±25.9 °C
• 精确质量: 234.046295
• PSA: 86.86000
• LogP: 1.25
• InChIKey: SYENTKHGMVKGAQ-UHFFFAOYSA-N
• SMILES: O=C(NC1CC1)c1cc(-c2cccs2)on1
• 外观性状: 粉末
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.637
• 储存条件: -20℃

ISX-9靶点实验

查看更多实验

实验名称：Inhibition of LIF/BMP2-mediated rat HCN cell differentiation into astrocytes at 25 uM 来源：ChEMBL 靶标：N/A External Id：CHEMBL1225025

实验名称：Induction of rat HCN cell differentiation assessed as induction of neuronal reporter ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1225024

实验名称：Induction of rat HCN cell differentiation assessed as induction of neuronal reporter ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1225023

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VER... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4513082

实验名称：Induction of rat HCN cell differentiation assessed as increase in GluR2 gene expressi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1225033

实验名称：Induction of rat HCN cell differentiation assessed as increase in neuroD gene express... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1225032

实验名称：Induction of rat HCN differentiation into Tuj1 neurons at 25 uM after 4 days 来源：ChEMBL 靶标：N/A External Id：CHEMBL1225031

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Cac... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4303805

实验名称：Inhibition of gliogenesis differentiation in rat HCN cells at 25 uM after 4 days 来源：ChEMBL 靶标：N/A External Id：CHEMBL1225030

实验名称：Induction of mouse progenitor cell differentiation into Tuj1 neurons at 20 uM after 4... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1225029

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ISX-9英文别名

• N-Cyclopropyl-5-(2-thienyl)-1,2-oxazole-3-carboxamide
• ISX 9
• Isoxazole 9
• ISX-9