8-chloro-10-phenylpyrimido[4,5-b]quinoline-2,4-dione

• 常用名: 8-chloro-10-phenylpyrimido[4,5-b]quinoline-2,4-dione
• 英文名: 8-chloro-10-phenylpyrimido[4,5-b]quinoline-2,4-dione
• CAS号: 84459-37-0
• 分子量: 323.73300
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₁₀ClN₃O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 8-chloro-10-phenylpyrimido[4,5-b]quinoline-2,4-dione

物理化学性质

• 分子式: C₁₇H₁₀ClN₃O₂
• 分子量: 323.73300
• 精确质量: 323.04600
• PSA: 68.01000
• LogP: 3.29290
• InChIKey: KUZXWHQMNCGRQX-UHFFFAOYSA-N
• SMILES: O=c1nc2n(-c3ccccc3)c3cc(Cl)ccc3cc-2c(=O)[nH]1

靶点实验

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实验名称：Stabilization of p53 in RPE cells at 1 uM after 24 hrs by Western blotting 来源：ChEMBL 靶标：Cellular tumor antigen p53 External Id：CHEMBL904416

实验名称：Stabilization of p53 in RPE cells at 5 to 10 uM after 24 hrs by Western blotting rela... 来源：ChEMBL 靶标：Cellular tumor antigen p53 External Id：CHEMBL904417

实验名称：Inhibition of TDP2 (unknown origin) using 4-nitrophenyl phenylphosphonate as substrat... 来源：ChEMBL 靶标：Tyrosyl-DNA phosphodiesterase 2 External Id：CHEMBL2423658

实验名称：Inhibition of APE-1 (unknown origin) using double-stranded AP-site containing DNA as ... 来源：ChEMBL 靶标：DNA-(apurinic or apyrimidinic site) endonuclease External Id：CHEMBL2423657

实验名称：Inhibition of TDP1 (unknown origin) using double-stranded AP-site containing DNA as s... 来源：ChEMBL 靶标：Tyrosyl-DNA phosphodiesterase 1 External Id：CHEMBL2423656

实验名称：Induction of redox cycling potential assessed as H2O2 production at 25 uM in presence... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2423456

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