N4-[3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-quinazoline-4,6-diamine

• 常用名: N4-[3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-quinazoline-4,6-diamine
• 英文名: N4-[3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-quinazoline-4,6-diamine
• CAS号: 845271-71-8
• 分子量: 394.82900
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₁₆ClFN₄O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N4-[3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-quinazoline-4,6-diamine

物理化学性质

• 分子式: C₂₁H₁₆ClFN₄O
• 分子量: 394.82900
• 精确质量: 394.10000
• PSA: 73.06000
• LogP: 5.98130
• InChIKey: FBSYJUVNGAMMOK-UHFFFAOYSA-N
• SMILES: Nc1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1

靶点实验

查看更多实验

实验名称：MRC5 CC50 (uM) Cytotoxicity 来源：ChEMBL 靶标：MRC5 External Id：CHEMBL3832842

实验名称：PMM CC50 (uM) Cytotoxicity 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3832843

实验名称：Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020);... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4296184

实验名称：Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ... 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL4296186

实验名称：AntiTrypanosoma cruzi activity IC50 (uM) 来源：ChEMBL 靶标：Trypanosoma cruzi External Id：CHEMBL3832785

实验名称：Antibacterial activity against Escherichia coli ATCC 25922 (CO-ADD:GN_001); MIC in CA... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL4296185

实验名称：AntiTrypanosoma brucei activity T. b. brucei IC50 (uM) 来源：ChEMBL 靶标：Trypanosoma brucei External Id：CHEMBL3832786

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：Compound was evaluated for the inhibition of human FECH at 10uM 来源：ChEMBL 靶标：Ferrochelatase, mitochondrial External Id：CHEMBL3987222

实验名称：Compound was evaluated for the inhibition of human HMBS at 100uM 来源：ChEMBL 靶标：Porphobilinogen deaminase External Id：CHEMBL3987223

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英文别名

• 4-[3-chloro-4-(3-fluoro-benzyloxy)-phenylamino]-6-amino-quinazoline
• 4-[3-chloro-4-(3-fluoro-benzyloxy)phenylamino]-6-amino-quinazoline
• N4-[3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-quinazolin-4,6-diamine
• 4-[3-chloro-4-(3-fluorobenzyloxy)phenylamino]-6-aminoquinazoline
• N4-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)quinazoline-4,6-diamine