N4-(3-Bromophenyl)-N6-(2-chloroethyl)-4,6-quinazolinediamine

• 常用名: N4-(3-Bromophenyl)-N6-(2-chloroethyl)-4,6-quinazolinediamine
• 英文名: N4-(3-Bromophenyl)-N6-(2-chloroethyl)-4,6-quinazolinediamine
• CAS号: 848352-60-3
• 分子量: 377.7
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₆H₁₄BrClN₄
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N4-(3-Bromophenyl)-N6-(2-chloroethyl)-4,6-quinazolinediamine

物理化学性质

• 分子式: C₁₆H₁₄BrClN₄
• 分子量: 377.7
• InChIKey: NPLZGCKBBUBACR-UHFFFAOYSA-N
• SMILES: ClCCNc1ccc2ncnc(Nc3cccc(Br)c3)c2c1

靶点实验

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实验名称：Binding affinity to calf thymus DNA assessed as compound hydrolysis at 10 mM after 5 ... 来源：ChEMBL 靶标：Calf thymus DNA External Id：CHEMBL4685755

实验名称：Binding affinity to calf thymus DNA assessed as guanine alkylated adduct formation at... 来源：ChEMBL 靶标：Calf thymus DNA External Id：CHEMBL4685757

实验名称：Binding affinity to calf thymus DNA assessed as adenine alkylated adduct formation at... 来源：ChEMBL 靶标：Calf thymus DNA External Id：CHEMBL4685756

实验名称：Induction of DNA damage in human A549 cells at 0.1 to 10 uM after 2 hrs by comet assa... 来源：ChEMBL 靶标：A549 External Id：CHEMBL4685758

实验名称：Inhibition of EGFR phosphorylation in human A549 cells at 1 to 10 uM preincubated for... 来源：ChEMBL 靶标：Epidermal growth factor receptor External Id：CHEMBL4685747

实验名称：Inhibition of EGFR phosphorylation in human PC-9 cells at 1 to 10 uM preincubated for... 来源：ChEMBL 靶标：Epidermal growth factor receptor External Id：CHEMBL4685746

实验名称：Inhibition of EGFR phosphorylation in human PC-9 cells assessed as downregulation MAP... 来源：ChEMBL 靶标：Epidermal growth factor receptor External Id：CHEMBL4685749

实验名称：Inhibition of EGFR phosphorylation in human A549 cells assessed as downregulation MAP... 来源：ChEMBL 靶标：Epidermal growth factor receptor External Id：CHEMBL4685751

实验名称：Inhibition of EGFR phosphorylation in human PC-9 cells assessed as downregulation AKT... 来源：ChEMBL 靶标：Epidermal growth factor receptor External Id：CHEMBL4685750

实验名称：Inhibition of EGFR phosphorylation in human A549 cells assessed as downregulation AKT... 来源：ChEMBL 靶标：Epidermal growth factor receptor External Id：CHEMBL4685752

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