(4-(5-(Tert-butyl)-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl)(furan-2-yl)methanone

• 常用名: (4-(5-(Tert-butyl)-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl)(furan-2-yl)methanone
• 英文名: (4-(5-(Tert-butyl)-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl)(furan-2-yl)methanone
• CAS号: 849920-43-0
• 分子量: 478.0
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₂₈ClN₅O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (4-(5-(Tert-butyl)-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl)(furan-2-yl)methanone

物理化学性质

• 分子式: C₂₆H₂₈ClN₅O₂
• 分子量: 478.0
• InChIKey: ZXFVSQCSNVZHQU-UHFFFAOYSA-N
• SMILES: CC1=NN2C(=CC(=NC2=C1C3=CC=C(C=C3)Cl)C(C)(C)C)N4CCN(CC4)C(=O)C5=CC=CO5

靶点实验

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实验名称：Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste... 来源：Broad Institute 靶标：N/A External Id：7124-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：HTS to identify inhibitors of TNF-alpha Induced Cell Death in Jurkat FADD-/- Cells. 来源：University of Pittsburgh Molecular Library Screening Center 靶标：N/A External Id：MH081226: Primary HTS for Inhibitors of a Novel Necrotic Cell Death Pathway # Jurkat FADD-/- Model.

实验名称：384-well Z-Lyte format Hck-Nef inhibitor HTS run at the PMLSC 来源：University of Pittsburgh Molecular Library Screening Center 靶标：N/A External Id：MH083223 Targeting HIV-1 Nef with Small Molecules

实验名称：High Throughput Screen to Identify Inhibitors Targeting HIV-1 Vif-dependent Degradati... 来源：Southern Research Institute 靶标：HIV-1 Vif External Id：HIV1-VIF_MS

实验名称：uHTS HTRF assay for identification of inhibitors of SUMOylation 来源：Burnham Center for Chemical Genomics 靶标：SUMO1 activating enzyme subunit 1 [Homo sapiens] External Id：BCCG-A235-SUMO-HTRF-Assay

实验名称：Dose Response for ABC transporter inhibitors: specifically ABCG2 screen, ABCB1 counte... 来源：NMMLSC 靶标：ATP-binding cassette sub-family G member 2 [Homo sapiens] External Id：UNMCMD_ABC_TRANSPORTERS_ABCG2_DOSE_RESPONSE_FOLLOW_UP

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：uHTS fluorescence polarization assay for the identification of translation initiation... 来源：Burnham Center for Chemical Genomics 靶标：Eukaryotic translation initiation factor 4H [Homo sapiens] External Id：BCCG-A237-eIF4H-FP-Assay

实验名称：Dose Response for ABC transporter inhibitors: specifically ABCB1 screen, ABCG2 counte... 来源：NMMLSC 靶标：multidrug resistance protein 1 [Homo sapiens] External Id：UNMCMD_ABC_TRANSPORTERS_ABCB1_DOSE_RESPONSE_FOLLOW_UP

实验名称：qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme ... 来源：NCGC 靶标：Luciferase [Photinus pyralis] External Id：FLUC100

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