1-Piperazineacetamide, 4-ethyl-N-[4-[[2-[[2-fluoro-5-(trifluoromethyl)phenyl]amino]-1-methyl-1H-benzimidazol-5-yl]oxy]-2-pyridinyl]

• 常用名: 1-Piperazineacetamide, 4-ethyl-N-[4-[[2-[[2-fluoro-5-(trifluoromethyl)phenyl]amino]-1-methyl-1H-benzimidazol-5-yl]oxy]-2-pyridinyl]
• 英文名: 1-Piperazineacetamide, 4-ethyl-N-[4-[[2-[[2-fluoro-5-(trifluoromethyl)phenyl]amino]-1-methyl-1H-benzimidazol-5-yl]oxy]-2-pyridinyl]
• CAS号: 850708-44-0
• 分子量: 571.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₈H₂₉F₄N₇O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 1-Piperazineacetamide, 4-ethyl-N-[4-[[2-[[2-fluoro-5-(trifluoromethyl)phenyl]amino]-1-methyl-1H-benzimidazol-5-yl]oxy]-2-pyridinyl]

物理化学性质

• 分子式: C₂₈H₂₉F₄N₇O₂
• 分子量: 571.6
• InChIKey: CXXTWUWDVIYTID-UHFFFAOYSA-N
• SMILES: CCN1CCN(CC(=O)Nc2cc(Oc3ccc4c(c3)nc(Nc3cc(C(F)(F)F)ccc3F)n4C)ccn2)CC1

靶点实验

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实验名称：Volume of distribution in rat at 10 mg/kg, po as single dose 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3384718

实验名称：Clearance in rat at 10 mg/kg, po as single dose 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3384717

实验名称：Oral bioavailability in rat at 10 mg/kg as single dose 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3384720

实验名称：Half life in rat at 10 mg/kg, po as single dose 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3384719

实验名称：Inhibition of SRC (unknown origin) 来源：ChEMBL 靶标：Proto-oncogene tyrosine-protein kinase Src External Id：CHEMBL3384725

实验名称：Antitumor activity against human HT-29 cells harboring B-RAF V600E mutant xenografted... 来源：ChEMBL 靶标：HT-29 External Id：CHEMBL3384728

实验名称：Antitumor activity against human HT-29 cells harboring B-RAF V600E mutant xenografted... 来源：ChEMBL 靶标：HT-29 External Id：CHEMBL3384727

实验名称：Toxicity in human HT-29 cells harboring B-RAF V600E mutant xenografted nude mouse ass... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3384730

实验名称：Antitumor activity against human HT-29 cells harboring B-RAF V600E mutant xenografted... 来源：ChEMBL 靶标：HT-29 External Id：CHEMBL3384729

实验名称：Toxicity in human HT-29 cells harboring B-RAF V600E mutant xenografted nude mouse ass... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3384732

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