1-ethyl-6-fluoro-7-[4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]piperazin-1-yl]-4-oxoquinoline-3-carboxylic acid

• 常用名: 1-ethyl-6-fluoro-7-[4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]piperazin-1-yl]-4-oxoquinoline-3-carboxylic acid
• 英文名: 1-ethyl-6-fluoro-7-[4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]piperazin-1-yl]-4-oxoquinoline-3-carboxylic acid
• CAS号: 85195-76-2
• 分子量: 431.41400
• 密度: 1.425g/cm3
• 沸点: 615ºC at 760 mmHg
• 分子式: C₂₁H₂₂FN₃O₆
• 熔点: N/A
• 闪点: 325.7ºC

名称

• 英文名: 1-ethyl-6-fluoro-7-[4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]piperazin-1-yl]-4-oxoquinoline-3-carboxylic acid

物理化学性质

• 密度: 1.425g/cm3
• 沸点: 615ºC at 760 mmHg
• 分子式: C₂₁H₂₂FN₃O₆
• 分子量: 431.41400
• 闪点: 325.7ºC
• 精确质量: 431.14900
• PSA: 109.13000
• LogP: 2.03840
• InChIKey: PLARREUCIWJWCL-UHFFFAOYSA-N
• SMILES: CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(Cc4oc(=O)oc4C)CC3)cc21
• 折射率: 1.611

靶点实验

查看更多实验

实验名称：Serum level of compound (50 mg/kg) after 0.25 hr of peroral administration in mice 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL875982

实验名称：Serum level of compound (50 mg/kg) after 0.50 hr of peroral administration in mice 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL630895

实验名称：Serum level of compound (50 mg/kg) after 1.0 hr of peroral administration in mice 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL630896

实验名称：Serum level of compound (50 mg/kg) after 2.0 hr of peroral administration in mice 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL630897

实验名称：Minimum inhibitory concentration tested against Bacillus subtilis ATCC 6633 来源：ChEMBL 靶标：Bacillus subtilis External Id：CHEMBL857911

实验名称：Serum level of compound (50 mg/kg) after 3.0 hh of peroral administration in mice 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL630898

实验名称：Area under curve value of compound per hour after oral administration 来源：ChEMBL 靶标：N/A External Id：CHEMBL624135

实验名称：Serum level of compound (50 mg/kg) after 4.0h of peroral administration in mice 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL630899

实验名称：Effective dose of compound against Escherichia coli KC-14 in rats after oral administ... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL674153

实验名称：Oral efficacy of compound after peroral administration on systemic infection by Esche... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL674154

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英文别名

• 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-(5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl-1-piperazinyl]quinoline-3-carboxylic acid
• N-(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl NFLX
• N-((5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl)norfloxacin
• 3-Quinolinecarboxylic acid,1,4-dihydro-1-ethyl-6-fluoro-7-(4-((5-methyl-2-oxo-1,3-dioxol-4-yl)methyl)-1-piperazinyl)-4-oxo