N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-5-yloxy)ethyl)-2-hydroxy-N-methylacetamide

• 常用名: N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-5-yloxy)ethyl)-2-hydroxy-N-methylacetamide
• 英文名: N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-5-yloxy)ethyl)-2-hydroxy-N-methylacetamide
• CAS号: 853000-40-5
• 分子量: 493.9
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₂₄ClN₅O₄
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-5-yloxy)ethyl)-2-hydroxy-N-methylacetamide

物理化学性质

• 分子式: C₂₅H₂₄ClN₅O₄
• 分子量: 493.9
• InChIKey: XNMHWKJRXNZELF-UHFFFAOYSA-N
• SMILES: CN(CCOc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)C(=O)CO

靶点实验

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实验名称：Ratio of drug level in mouse plasma after 6 hrs in presence of 1-aminobenzotriazole t... 来源：ChEMBL 靶标：Nucleic Acid External Id：CHEMBL925244

实验名称：Ratio of drug level in mouse plasma after 16 hrs in presence of 1-aminobenzotriazole ... 来源：ChEMBL 靶标：Nucleic Acid External Id：CHEMBL925245

实验名称：Ratio of drug level in mouse plasma after 24 hrs in presence of 1-aminobenzotriazole ... 来源：ChEMBL 靶标：Nucleic Acid External Id：CHEMBL925246

实验名称：Ratio of drug level in mouse plasma after 2 hrs in presence of 1-aminobenzotriazole t... 来源：ChEMBL 靶标：Nucleic Acid External Id：CHEMBL925242

实验名称：Ratio of drug level in mouse plasma after 4 hrs in presence of 1-aminobenzotriazole t... 来源：ChEMBL 靶标：Nucleic Acid External Id：CHEMBL925243

实验名称：Ratio of drug level in mouse plasma after 24 hrs in presence of 1-aminobenzotriazole ... 来源：ChEMBL 靶标：Nucleic Acid External Id：CHEMBL925248

实验名称：AUC in mouse at 50 mg/kg, po in presence of 1-aminobenzotriazole 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL925249

实验名称：In vivo phospholipidosis in rat after 14 days at 600 mg/kg dose q.d. 来源：ChEMBL 靶标：Phospholipidosis External Id：CHEMBL925250

实验名称：Antitumor activity against human BT474C cells xenografted mouse at 50 mg/kg, po qd fo... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL925251

实验名称：Ratio of drug level in mouse plasma after 2 hrs in presence of 1-aminobenzotriazole t... 来源：ChEMBL 靶标：Nucleic Acid External Id：CHEMBL924189

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