4-(1-(4-羟基-3-甲氧基苄基)-1H-苯并[d]咪唑-2-基)-2-甲氧基苯酚

• 常用名: 4-(1-(4-羟基-3-甲氧基苄基)-1H-苯并[d]咪唑-2-基)-2-甲氧基苯酚
• 英文名: ATPase-IN-2
• CAS号: 85573-18-8
• 分子量: 376.41
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₂₀N₂O₄
• 熔点: N/A
• 闪点: N/A

用途

ATP酶-IN-2是一种ATP酶抑制剂,其IC50值为0.9μM。ATP酶-IN-2抑制艰难梭菌毒素B(TcdB)糖水解酶活性,AC50值为30.91μM。ATP酶-IN-2可用于ATP相关的研究[1]。

名称

• 中文名: 4-(1-(4-羟基-3-甲氧基苄基)-1H-苯并[d]咪唑-2-基)-2-甲氧基苯酚
• 英文名: 4-(1-(4-Hydroxy-3-methoxybenzyl)-1H-benzo[d]imidazol-2-yl)-2-methoxyphenol

生物活性

• 描述: ATP酶-IN-2是一种ATP酶抑制剂,其IC50值为0.9μM。ATP酶-IN-2抑制艰难梭菌毒素B(TcdB)糖水解酶活性,AC50值为30.91μM。ATP酶-IN-2可用于ATP相关的研究[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 靶点实验:

  IC50: 0.9 μM (ATPase)[1]

• 参考文献:

  [1]. Jeffery Brodsky, et al. Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents. 2010.

物理化学性质

• 分子式: C₂₂H₂₀N₂O₄
• 分子量: 376.41
• InChIKey: SBVOOAOEAYENPN-UHFFFAOYSA-N
• SMILES: COc1cc(Cn2c(-c3ccc(O)c(OC)c3)nc3ccccc32)ccc1O
• 储存条件: -20°C

靶点实验

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英文别名

• MFCD01952969