ONO-0300302结构式
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常用名 | ONO-0300302 | 英文名 | ONO-0300302 |
|---|---|---|---|---|
| CAS号 | 856689-51-5 | 分子量 | 477.601 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C29H35NO5 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | N/A |
ONO-0300302用途ONO-0300302(ONO0300302)是一种新型有效,缓慢紧密结合的LPA1受体拮抗剂,IC50为86 nM,Kd为0.34 nM;显示出优异的体内功效,是LPA相关疾病可用的最佳研究工具。 |
| 英文名 | ONO-0300302 |
|---|
| 描述 | ONO-0300302(ONO0300302)是一种新型有效,缓慢紧密结合的LPA1受体拮抗剂,IC50为86 nM,Kd为0.34 nM;显示出优异的体内功效,是LPA相关疾病可用的最佳研究工具。 |
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| 参考文献 | References 1. Masahiko Terakado, et al. ACS Med. Chem. Lett., 2017, 8 (12), pp 1281-1286. View Related Products by Target Lysophospholipid Receptor |
| 分子式 | C29H35NO5 |
|---|---|
| 分子量 | 477.601 |
| InChIKey | USAXUWZJQPBEDO-ABYGYWHVSA-N |
| SMILES | COc1cc(C(O)C(CC2Cc3ccccc3C2)Cn2ccc(CCC(=O)O)c2)cc(OC)c1C |
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实验名称:Inhibition of LPA-induced increase of intraurethral pressure in dog at 1 to 3 mg/kg, ...
来源:ChEMBL
靶标:Canis lupus familiaris
External Id:CHEMBL4144015
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实验名称:Antagonist activity at recombinant human LPA1 expressed in CHO cells assessed as redu...
来源:ChEMBL
靶标:Lysophosphatidic acid receptor 1
External Id:CHEMBL4144007
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实验名称:Inhibition of LPA-induced increase of intraurethral pressure in rat at 3 mg/kg, po me...
来源:ChEMBL
靶标:Rattus norvegicus
External Id:CHEMBL4144020
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实验名称:Inhibition of LPA-induced increase of intraurethral pressure in dog at 1 mg/kg, po me...
来源:ChEMBL
靶标:Canis lupus familiaris
External Id:CHEMBL4144021
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