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3-(1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione

更新时间:2025-08-23 12:09:13

3-(1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione结构式
3-(1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione结构式
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常用名 3-(1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione 英文名 3-(1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione
CAS号 863223-52-3 分子量 378.37800
密度 N/A 沸点 N/A
分子式 C21H18N2O5 熔点 N/A
MSDS N/A 闪点 N/A

 名称

英文名 3-(1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione
英文别名 更多

 物理化学性质

分子式 C21H18N2O5
分子量 378.37800
精确质量 378.12200
PSA 93.14000
LogP 3.03680
InChIKey CZGMEOAMQWAJOY-UHFFFAOYSA-N
SMILES COc1cc(C2=C(c3c[nH]c4ccccc34)C(=O)NC2=O)cc(OC)c1OC

 合成线路

~79%

3-(1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione结构式

3-(1H-indol-3-y...

863223-52-3

文献:Ilovich, Ohad; Billauer, Hana; Dotan, Sharon; Mishani, Eyal Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 2 p. 612 - 620

~72%

3-(1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione结构式

3-(1H-indol-3-y...

863223-52-3

文献:Peifer, Christian; Selig, Roland; Kinkel, Katrin; Ott, Dimitri; Totzke, Frank; Schaechtele, Christoph; Heidenreich, Regina; Roecken, Martin; Schollmeyer, Dieter; Laufer, Stefan Journal of Medicinal Chemistry, 2008 , vol. 51, # 13 p. 3814 - 3824

~%

3-(1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione结构式

3-(1H-indol-3-y...

863223-52-3

文献:Peifer, Christian; Krasowski, Agata; Haemmerle, Nina; Kohlbacher, Oliver; Dannhardt, Gerd; Totzke, Frank; Schaechtele, Christoph; Laufer, Stefan Journal of Medicinal Chemistry, 2006 , vol. 49, # 25 p. 7549 - 7553

 靶点实验

查看更多实验

实验名称:Inhibition of VEGFR2
来源:ChEMBL
靶标:Vascular endothelial growth factor receptor 2
External Id:CHEMBL939341
实验名称:Inhibition of human recombinant IGF1R
来源:ChEMBL
靶标:Insulin-like growth factor 1 receptor
External Id:CHEMBL957970
实验名称:Inhibition of human recombinant CDK4/cyclin D1
来源:ChEMBL
靶标:Cyclin-dependent kinase 4
External Id:CHEMBL957971
实验名称:Inhibition of human recombinant CDK2/cyclin A
来源:ChEMBL
靶标:Cyclin-dependent kinase 2
External Id:CHEMBL957969
实验名称:Inhibition of human recombinant Aurora A
来源:ChEMBL
靶标:Aurora kinase A
External Id:CHEMBL962087
实验名称:Inhibition of human recombinant Aurora B
来源:ChEMBL
靶标:Aurora kinase B
External Id:CHEMBL962088
实验名称:Inhibition of human recombinant ARK5
来源:ChEMBL
靶标:NUAK family SNF1-like kinase 1
External Id:CHEMBL962086
实验名称:Inhibition of human recombinant VEGFR3
来源:ChEMBL
靶标:Vascular endothelial growth factor receptor 3
External Id:CHEMBL957978
实验名称:Inhibition of human recombinant FLT3
来源:ChEMBL
靶标:Receptor-type tyrosine-protein kinase FLT3
External Id:CHEMBL957979
实验名称:Inhibition of human recombinant SRC
来源:ChEMBL
靶标:Proto-oncogene tyrosine-protein kinase Src
External Id:CHEMBL957976
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 英文别名

3-(indole-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-pyrrole-2,5-dione
3-(1H-indol-3-yl)-(3,4,5-trimethoxyphenyl)-1H-pyrrole-2,5-dione
1H-Pyrrole-2,5-dione,3-(1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)
3-(1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-pyrrole-2,5-dione
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