Butanamide, N-(5,6,7,9-tetrahydro-1,2,3, 10-tetramethyloxy-9-oxobenzo[a]heptalen-7-yl)-, (S)

• 常用名: Butanamide, N-(5,6,7,9-tetrahydro-1,2,3, 10-tetramethyloxy-9-oxobenzo[a]heptalen-7-yl)-, (S)
• 英文名: Butanamide, N-(5,6,7,9-tetrahydro-1,2,3, 10-tetramethyloxy-9-oxobenzo[a]heptalen-7-yl)-, (S)
• CAS号: 86436-36-4
• 分子量: 427.49000
• 密度: 1.22g/cm3
• 沸点: 731.5ºC at 760 mmHg
• 分子式: C₂₄H₂₉NO₆
• 熔点: N/A
• 闪点: 396.2ºC

名称

• 英文名: N-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)butanamide

物理化学性质

• 密度: 1.22g/cm3
• 沸点: 731.5ºC at 760 mmHg
• 分子式: C₂₄H₂₉NO₆
• 分子量: 427.49000
• 闪点: 396.2ºC
• 精确质量: 427.19900
• PSA: 83.09000
• LogP: 4.04270
• InChIKey: XWHJWSRKXWWZRN-KRWDZBQOSA-N
• SMILES: CCCC(=O)NC1CCc2cc(OC)c(OC)c(OC)c2-c2ccc(OC)c(=O)cc21
• 折射率: 1.575

毒性和生态

靶点实验

查看更多实验

实验名称：Potency against lymphocytic leukemia P388 screen in mice. 来源：ChEMBL 靶标：P388 External Id：CHEMBL760580

实验名称：Selectivity index, ratio of IC50 for HEK293 cells to IC50 for human HT-29 cells 来源：ChEMBL 靶标：N/A External Id：CHEMBL3998367

实验名称：Toxicity in the P388 NCI screen defined as the dose that caused an average wt. loss>3... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL727960

实验名称：Cytotoxicity against HEK293 cells assessed as growth inhibition after 72 hrs by MTT a... 来源：ChEMBL 靶标：HEK293 External Id：CHEMBL3998366

实验名称：Toxicity found after a single intramuscular injection in mice 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL727959

实验名称：Selectivity index, ratio of IC50 for HEK293 cells to IC50 for human MCF7 cells 来源：ChEMBL 靶标：N/A External Id：CHEMBL3998368

实验名称：Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by M... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL3998365

实验名称：Percentage by which binding is reduced at 25 uM in rat brain microtubule protein 来源：ChEMBL 靶标：Tubulin alpha-3C chain External Id：CHEMBL820638

实验名称：Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by ... 来源：ChEMBL 靶标：HT-29 External Id：CHEMBL3998364

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英文别名

• Butanamide,N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethyloxy-9-oxobenzo(a)heptalen-7-yl)-,(S)
• Butanamide,6,7,9-tetrahydro-1,2,3,10-tetramethyloxy-9-oxobenzo[a]heptalen-7-yl)-,(S)
• N-butyryldeacetylcolchicine
• (S)-N-(5,6,7,9-TETRAHYDRO-1,2,3,10-TETRAMETHYLOXY-9-OXOBENZO[A]HEPTALEN-7-YL)BUTANAMIDE