3-Cyclobutyl-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine

• 常用名: 3-Cyclobutyl-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
• 英文名: 3-Cyclobutyl-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
• CAS号: 867160-41-6
• 分子量: 391.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₂₁N₅
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3-Cyclobutyl-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine

物理化学性质

• 分子式: C₂₅H₂₁N₅
• 分子量: 391.5
• InChIKey: LFQVOSHWRZTZHW-UHFFFAOYSA-N
• SMILES: Nc1nccn2c(C3CCC3)nc(-c3ccc4ccc(-c5ccccc5)nc4c3)c12

靶点实验

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实验名称：Extraction ratio of of hepatic clearance to hepatic blood flow in mouse microsomes 来源：ChEMBL 靶标：N/A External Id：CHEMBL1695280

实验名称：Extraction ratio of of hepatic clearance to hepatic blood flow in human microsomes 来源：ChEMBL 靶标：N/A External Id：CHEMBL1695281

实验名称：Inhibition of human mTORC1/2 expressed in HeLa cells assessed as inhibition of 4E-BP1... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1762890

实验名称：AUC (0 to infinity) in CD-1 mouse at 50 mg/kg, po measured after 1 to 24 hrs by HPLC-... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5664294

实验名称：Oral bioavailability in CD-1 mouse administered at 50 mg/kg measured after 1 to 24 hr... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5664295

实验名称：Microsomal stability in human liver microsomes assessed as extraction ratio in presen... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5664298

实验名称：Microsomal stability in mouse liver microsomes assessed as extraction ratio in presen... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5664299

实验名称：Elimination half life in CD-1 mouse at 5 mg/kg, iv measured after 1 to 24 hrs by HPLC... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5664300

实验名称：Volume of distribution at steady state in CD-1 mouse at 5 mg/kg, iv measured after 1 ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5664301

实验名称：Inhibition of auto-phosphorylation of human IGF1R expressed in mouse NIH-3T3 cells af... 来源：ChEMBL 靶标：Insulin-like growth factor 1 receptor External Id：CHEMBL1695277

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