(2Z)-2-benzylidene-6-hydroxy-7-(piperidin-1-ylmethyl)-1-benzofuran-3(2H)-one

• 常用名: (2Z)-2-benzylidene-6-hydroxy-7-(piperidin-1-ylmethyl)-1-benzofuran-3(2H)-one
• 英文名: (2Z)-2-benzylidene-6-hydroxy-7-(piperidin-1-ylmethyl)-1-benzofuran-3(2H)-one
• CAS号: 869077-43-0
• 分子量: 335.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₁NO₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (2Z)-2-benzylidene-6-hydroxy-7-(piperidin-1-ylmethyl)-1-benzofuran-3(2H)-one

物理化学性质

• 分子式: C₂₁H₂₁NO₃
• 分子量: 335.4
• InChIKey: KGKUOWSOZHXCPL-UYRXBGFRSA-N
• SMILES: C1CCN(CC1)CC2=C(C=CC3=C2O/C(=C\C4=CC=CC=C4)/C3=O)O

靶点实验

查看更多实验

实验名称：NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in... 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL1040691

实验名称：Cytotoxicity against HEK293T cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：HEK-293T External Id：CHEMBL3268301

实验名称：Antiplasmodial activity against chloroquine-resistant ring stage Plasmodium falciparu... 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL3268300

实验名称：Water-lipid distribution coefficient, log D of the compound at pH 7.4 来源：ChEMBL 靶标：N/A External Id：CHEMBL3268303

实验名称：Selectivity index, ratio of EC50 for HEK293T cells to IC50 for chloroquine-resistant ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3268302

实验名称：Vacuolar accumulation ratio of the compound 来源：ChEMBL 靶标：N/A External Id：CHEMBL3268305

实验名称：Water-lipid distribution coefficient, log D of the compound at pH 5.2 来源：ChEMBL 靶标：N/A External Id：CHEMBL3268304

实验名称：Inhibition of hemozoin-like crystal formation up to 1 mM after 5 days 来源：ChEMBL 靶标：N/A External Id：CHEMBL3268307

实验名称：Lipid accumulation ratio of the compound 来源：ChEMBL 靶标：N/A External Id：CHEMBL3268306

实验名称：NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compoun... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1040694

共16条，当前第1页，共2页

1

2