3-(3-chlorophenyl)-N-(tetrahydro-2H-pyran-4-yl)imidazo[1,2-b]pyridazin-6-amine

• 常用名: 3-(3-chlorophenyl)-N-(tetrahydro-2H-pyran-4-yl)imidazo[1,2-b]pyridazin-6-amine
• 英文名: 3-(3-chlorophenyl)-N-(tetrahydro-2H-pyran-4-yl)imidazo[1,2-b]pyridazin-6-amine
• CAS号: 869650-22-6
• 分子量: 328.8
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₁₇ClN₄O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3-(3-chlorophenyl)-N-(tetrahydro-2H-pyran-4-yl)imidazo[1,2-b]pyridazin-6-amine

物理化学性质

• 分子式: C₁₇H₁₇ClN₄O
• 分子量: 328.8
• InChIKey: OEIWNDGDGDPXIO-UHFFFAOYSA-N
• SMILES: C1COCCC1NC2=NN3C(=NC=C3C4=CC(=CC=C4)Cl)C=C2

靶点实验

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实验名称：hERG Activity Assays from US Patent US10047093: "Substituted imidazo[1,2-B]pyridazine... 来源：BindingDB 靶标：N/A External Id：BindingDB_218_2

实验名称：Pim-1 Kinase Inhibition Assay from US Patent US10047093: "Substituted imidazo[1,2-B]p... 来源：BindingDB 靶标：N/A External Id：BindingDB_218_1

实验名称：ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake fl... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301363

实验名称：ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with wh... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301365

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：Kinase Inhibition Assay from Article 10.1158/0008-5472.CAN-07-0320: "Structural analy... 来源：BindingDB 靶标：N/A External Id：BindingDB_3459_1

实验名称：ASTRAZENECA: Intrinsic clearance measured in rat hepatocytes following incubation at ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301371

实验名称：ASTRAZENECA: Intrinsic clearance measured in human liver microsomes following incubat... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301370

实验名称：Inhibitory activity against PIM1 at 1 uM 来源：ChEMBL 靶标：Serine/threonine-protein kinase pim-1 External Id：CHEMBL862675

实验名称：Pim-1 Kinase Inhibition Assay from US Patent US10875864: "Substituted imidazo[1,2-B]p... 来源：BindingDB 靶标：N/A External Id：BindingDB_9603_1

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