4-二甲基氨基-7-(4-乙基-苯基)-7H-9-硫-1,5,7-三氮杂芴-8-酮

更新时间：2025-10-08 05:41:35

4-二甲基氨基-7-(4-乙基-苯基)-7H-9-硫-1,5,7-三氮杂芴-8-酮结构式	常用名	4-二甲基氨基-7-(4-乙基-苯基)-7H-9-硫-1,5,7-三氮杂芴-8-酮	英文名	4-DIMETHYLAMINO-7-(4-ETHYL-PHENYL)-7H-9-THIA-1,5,7-TRIAZA-FLUOREN-8-ONE
	CAS号	869802-44-8	分子量	350.43700
	密度	N/A	沸点	N/A
	分子式	C₁₉H₁₈N₄OS	熔点	N/A
	MSDS	N/A	闪点	N/A

中文名	4-二甲基氨基-7-(4-乙基-苯基)-7H-9-硫-1,5,7-三氮杂芴-8-酮
英文名	9-(dimethylamino)-3-(4-ethylphenyl)pyrido[1,2]thieno[3,4-d]pyrimidin-4-one
英文别名	更多

分子式	C₁₉H₁₈N₄OS
分子量	350.43700
精确质量	350.12000
PSA	79.26000
LogP	3.62380
InChIKey	VCUKKMIXURRDKL-UHFFFAOYSA-N
SMILES	CCc1ccc(-n2cnc3c(sc4nccc(N(C)C)c43)c2=O)cc1

海关编码	2934999090

3-AMINO-4-DIMET...

331857-03-5

4-二甲基氨基-7-(4-乙基...

869802-44-8

文献：Zheng, Guo Zhu; Bhatia, Pramila; Kolasa, Teodozyj; Patel, Meena; El Kouhen, Odile F.; Chang, Renjie; Uchic, Marie E.; Miller, Loan; Baker, Scott; Lehto, Sonya G.; Honore, Prisca; Wetter, Jill M.; Marsh, Kennan C.; Moreland, Robert B.; Brioni, Jorge D.; Stewart, Andrew O. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 18 p. 4936 - 4940

2-(1-(DIMETHYLA...

14164-26-2

4-二甲基氨基-7-(4-乙基...

869802-44-8

文献：Zheng, Guo Zhu; Bhatia, Pramila; Daanen, Jerome; Kolasa, Teodozyj; Patel, Meena; Latshaw, Steven; El Kouhen, Odile F.; Chang, Renjie; Uchic, Marie E.; Miller, Loan; Nakane, Masaki; Lehto, Sonya G.; Honore, Marie P.; Moreland, Robert B.; Brioni, Jorge D.; Stewart, Andrew O. Journal of Medicinal Chemistry, 2005 , vol. 48, # 23 p. 7374 - 7388

2-[1,3-双(二甲基氨基)...

91945-90-3

4-二甲基氨基-7-(4-乙基...

869802-44-8

2-氯-4-(二甲基氨基)烟腈

147992-80-1

4-二甲基氨基-7-(4-乙基...

869802-44-8

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

实验名称：Effect on pain in ip dosed rat in late phase of formalin assay
来源：ChEMBL
靶标：Rattus norvegicus
External Id：CHEMBL945127

实验名称：Effect on CFA-induced hyperalgesia in ip dosed rat
来源：ChEMBL
靶标：Rattus norvegicus
External Id：CHEMBL945128

实验名称：Effect on carrageenan model of inflammatory pain in ip dosed rat
来源：ChEMBL
靶标：Rattus norvegicus
External Id：CHEMBL945129

实验名称：Bioavailability in orally dosed rat
来源：ChEMBL
靶标：Rattus norvegicus
External Id：CHEMBL916412

实验名称：Selectivity for rat mGluR1 over rat mGluR5
来源：ChEMBL
靶标：N/A
External Id：CHEMBL916858

实验名称：Human mGlu1 receptor (Metabotropic glutamate receptors)
来源：IUPHAR-DB
靶标：mGlu1 receptor (Metabotropic glutamate receptors) [Homo sapiens]
External Id：289_Human

实验名称：Rat mGlu1 receptor (Metabotropic glutamate receptors)
来源：IUPHAR-DB
靶标：mGlu1 receptor (Metabotropic glutamate receptors) [Rattus norvegicus]
External Id：289_Rat

实验名称：Displacement of [3H]MPEP from rat cortex mGluR5
来源：ChEMBL
靶标：Metabotropic glutamate receptor 5
External Id：CHEMBL916418

实验名称：Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L...
来源：ChEMBL
靶标：Metabotropic glutamate receptor 1
External Id：CHEMBL916419

实验名称：Antagonist activity at human mGluR5 expressed in 1321N1 cells assessed as effect on L...
来源：ChEMBL
靶标：Metabotropic glutamate receptor 5
External Id：CHEMBL916420

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9-dimethylamino-3-(4-ethylphenyl)-3H-5-thia-1,3,6-triazafluoren-4-one

4-Dimethylamino-7-(4-ethyl-phenyl)-7H-9-thia-1,5,7-triaza-fluoren-8-one