3-[2-(4-Methoxyphenyl)-2-oxoethyl]-5,5-diphenylimidazolidine-2,4-dione

• 常用名: 3-[2-(4-Methoxyphenyl)-2-oxoethyl]-5,5-diphenylimidazolidine-2,4-dione
• 英文名: 3-[2-(4-Methoxyphenyl)-2-oxoethyl]-5,5-diphenylimidazolidine-2,4-dione
• CAS号: 871218-82-5
• 分子量: 400.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₂₀N₂O₄
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3-[2-(4-Methoxyphenyl)-2-oxoethyl]-5,5-diphenylimidazolidine-2,4-dione

物理化学性质

• 分子式: C₂₄H₂₀N₂O₄
• 分子量: 400.4
• InChIKey: BZIXIEVSXWQXTK-UHFFFAOYSA-N
• SMILES: COC1=CC=C(C=C1)C(=O)CN2C(=O)C(NC2=O)(C3=CC=CC=C3)C4=CC=CC=C4

靶点实验

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实验名称：Selectivity index, ratio of IC50 for ovine COX1 to IC50 for ovine COX2 来源：ChEMBL 靶标：N/A External Id：CHEMBL3788343

实验名称：Antibacterial activity against Escherichia coli ATCC 25922 assessed as bacterial grow... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL5150384

实验名称：Antibacterial activity against Escherichia coli Delta tolC assessed as bacterial grow... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL5150385

实验名称：NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L... 来源：DTP/NCI 靶标：N/A External Id：MCF7_OneDose

实验名称：NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell... 来源：DTP/NCI 靶标：N/A External Id：IGROV1_OneDose

实验名称：Binding affinity to bacterial LpxA assessed as dissociation constant 来源：ChEMBL 靶标：N/A External Id：CHEMBL5150380

实验名称：Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production p... 来源：ChEMBL 靶标：Prostaglandin G/H synthase 2 External Id：CHEMBL3788342

实验名称：Inhibition of ovine COX1 preincubated for 5 mins followed by addition of arachidonic ... 来源：ChEMBL 靶标：Prostaglandin G/H synthase 1 External Id：CHEMBL3788341

实验名称：Analgesic activity in ip dosed albino Swiss mouse assessed as reduction in licking an... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3788340

实验名称：Antiinflammatory activity in ip dosed Sprague-Dawley rat assessed as inhibition of ca... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3788339

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