3-(5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)-N-(2,4-difluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine

• 常用名: 3-(5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)-N-(2,4-difluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine
• 英文名: 3-(5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)-N-(2,4-difluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine
• CAS号: 872513-33-2
• 分子量: 434.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₀F₂N₆O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3-(5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)-N-(2,4-difluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine

物理化学性质

• 分子式: C₂₃H₂₀F₂N₆O
• 分子量: 434.4
• InChIKey: OAVQAUQHQJNYKR-UHFFFAOYSA-N
• SMILES: COc1ccc(C#CC(C)(C)N)cc1-c1[nH]nc2nc(Nc3ccc(F)cc3F)ncc12

靶点实验

查看更多实验

实验名称：Inhibition of collagen-induced arthritis in rat at 10 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL863444

实验名称：Inhibition of adjuvant-induced arthritis in rat at 25 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL863442

实验名称：Inhibition of LPS-induced TNFalpha release in mouse at 20 mg/kg, po 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL863440

实验名称：Inhibitory activity against murine p38-alpha MAPK 来源：ChEMBL 靶标：Mitogen-activated protein kinase 14 External Id：CHEMBL863439

实验名称：AUC in rat 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL863534

实验名称：Oral bioavailability in rat 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL863533

实验名称：Inhibition of CDK1 at 10 uM 来源：ChEMBL 靶标：Cyclin-dependent kinase 1 External Id：CHEMBL863536

实验名称：Inhibition of KDR at 10 uM 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 2 External Id：CHEMBL863466

实验名称：Inhibition of c-Src at 10 uM 来源：ChEMBL 靶标：Proto-oncogene tyrosine-protein kinase Src External Id：CHEMBL861787

实验名称：Inhibition of c-Abl at 10 uM 来源：ChEMBL 靶标：Tyrosine-protein kinase ABL1 External Id：CHEMBL863539

共13条，当前第1页，共2页

1

2