4-Oxo-n-(5-tert-butyl-1h-indol-6-yl)-1h-quinoline-3-carboxamide

• 常用名: 4-Oxo-n-(5-tert-butyl-1h-indol-6-yl)-1h-quinoline-3-carboxamide
• 英文名: 4-Oxo-n-(5-tert-butyl-1h-indol-6-yl)-1h-quinoline-3-carboxamide
• CAS号: 873053-92-0
• 分子量: 359.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₂₁N₃O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-Oxo-n-(5-tert-butyl-1h-indol-6-yl)-1h-quinoline-3-carboxamide

物理化学性质

• 分子式: C₂₂H₂₁N₃O₂
• 分子量: 359.4
• InChIKey: QPRWKGNEIQULEK-UHFFFAOYSA-N
• SMILES: CC(C)(C)c1cc2cc[nH]c2cc1NC(=O)c1c[nH]c2ccccc2c1=O

靶点实验

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实验名称：Potentiation of human CFTR F508del/G551D mutant in human bronchial epithelial cells b... 来源：ChEMBL 靶标：Cystic fibrosis transmembrane conductance regulator External Id：CHEMBL3385212

实验名称：AUC (0 to infinity) in Sprague-Dawley rat at 2.49 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3385215

实验名称：Volume of distribution at steady state in Sprague-Dawley rat at 2.49 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3385233

实验名称：Clearance in Sprague-Dawley rat at 2.49 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3385221

实验名称：Potentiation of human CFTR F508del mutant expressed in mouse NIH-3T3 cells after 30 m... 来源：ChEMBL 靶标：Cystic fibrosis transmembrane conductance regulator External Id：CHEMBL3382095

实验名称：Half life in Sprague-Dawley rat at 2.49 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3385227

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