(S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl-N-((tetrahydrofuran-2-yl)methyl)furo[2,3-d]pyrimidin-4-amine

• 常用名: (S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl-N-((tetrahydrofuran-2-yl)methyl)furo[2,3-d]pyrimidin-4-amine
• 英文名: (S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl-N-((tetrahydrofuran-2-yl)methyl)furo[2,3-d]pyrimidin-4-amine
• CAS号: 873305-36-3
• 分子量: 458.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₃₀N₄O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl-N-((tetrahydrofuran-2-yl)methyl)furo[2,3-d]pyrimidin-4-amine

物理化学性质

• 分子式: C₂₇H₃₀N₄O₃
• 分子量: 458.6
• InChIKey: XNSZHQUDPHATEN-QFIPXVFZSA-N
• SMILES: CN(C)CCOc1ccc(-c2oc3ncnc(NCC4CCCO4)c3c2-c2ccccc2)cc1

靶点实验

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实验名称：Inhibition of N-terminal His6-tagged ACK1 expressed in baculovirus infected Hi5 cells... 来源：ChEMBL 靶标：Activated CDC42 kinase 1 External Id：CHEMBL2090703

实验名称：Inhibition of ACK1 in mouse C8 cells assessed as decrease in cell viability after 20 ... 来源：ChEMBL 靶标：Activated CDC42 kinase 1 External Id：CHEMBL2090704

实验名称：Inhibition of Lck 来源：ChEMBL 靶标：Tyrosine-protein kinase Lck External Id：CHEMBL902547

实验名称：Inhibition of T cell activation in human mixed lymphocyte reaction 来源：ChEMBL 靶标：T-cell External Id：CHEMBL902548

实验名称：Inhibition of anti-CD3/CD28-induced IL2 secretion in human T cells 来源：ChEMBL 靶标：T-cell External Id：CHEMBL902549

实验名称：Inhibition of ACK1 kinase (unknown origin) 来源：ChEMBL 靶标：Activated CDC42 kinase 1 External Id：CHEMBL3429155

实验名称：ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake fl... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301363

实验名称：Inhibition of Ack1 来源：ChEMBL 靶标：Activated CDC42 kinase 1 External Id：CHEMBL903634

实验名称：ASTRAZENECA: Solubility in pH7.4 buffer using solid starting material using the metho... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301364

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