GSK-588045

• 常用名: GSK-588045
• 英文名: GSK-588045
• CAS号: 876922-98-4
• 分子量: 468.55000
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₂₈N₆O₂
• 熔点: N/A
• 闪点: N/A

GSK-588045名称

• 英文名: 6-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}-4H-imidazo[5 ,1-c][1,4]benzoxazine-3-carboxamide

GSK-588045物理化学性质

• 分子式: C₂₇H₂₈N₆O₂
• 分子量: 468.55000
• 精确质量: 468.22700
• PSA: 90.50000
• LogP: 3.97200
• InChIKey: HLQJZFFWUXHYMB-UHFFFAOYSA-N
• SMILES: Cc1ccc2c(N3CCN(CCc4cccc5c4OCc4c(C(N)=O)ncn4-5)CC3)cccc2n1

GSK-588045靶点实验

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实验名称：Antihypothermic activity in po dosed Dunkin Hartley guinea pig assessed as reversal o... 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL1248781

实验名称：Antihypothermic activity in po dosed Dunkin Hartley guinea pig assessed as steady sta... 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL1248780

实验名称：Antihyperlocomotion activity in po dosed Sprague-Dawley rat assessed as steady state ... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1248779

实验名称：Antihyperlocomotion activity in po dosed Sprague-Dawley rat assessed as reversal of 8... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1248778

实验名称：Ex vivo receptor occupancy of 5HT1B receptor in po dosed Dunkin Hartley guinea pig br... 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL1248785

实验名称：Ex vivo receptor occupancy of 5HT1A receptor in po dosed Dunkin Hartley guinea pig br... 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL1248784

实验名称：Ex vivo receptor occupancy of 5HT1B receptor in po dosed Dunkin Hartley guinea pig br... 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL1248783

实验名称：Ex vivo receptor occupancy of 5HT1A receptor in po dosed Dunkin Hartley guinea pig br... 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL1248782

实验名称：Inhibition of human recombinant CYP1A2 preincubated for 10 mins 来源：ChEMBL 靶标：Cytochrome P450 1A2 External Id：CHEMBL1248094

实验名称：Antagonist activity against human recombinant 5HT1D receptor expressed in CHO cells a... 来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1D External Id：CHEMBL1248647

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GSK-588045英文别名

• Methylhydrasteine methyl ester
• N-methylhydrasteine methyl ester
• GSK-588045