洛索蒽醌

• 常用名: 洛索蒽醌
• 英文名: Losoxantrone
• CAS号: 88303-60-0
• 分子量: 425.48100
• 密度: 1.46g/cm3
• 沸点: 765.2ºC at 760 mmHg
• 分子式: C₂₂H₂₇N₅O₄
• 熔点: N/A
• 闪点: 416.6ºC

洛索蒽醌名称

• 中文名: 洛索蒽醌
• 英文名: Losoxantrone

洛索蒽醌物理化学性质

• 密度: 1.46g/cm3
• 沸点: 765.2ºC at 760 mmHg
• 分子式: C₂₂H₂₇N₅O₄
• 分子量: 425.48100
• 闪点: 416.6ºC
• 精确质量: 425.20600
• PSA: 131.67000
• LogP: 1.27680
• InChIKey: YROQEQPFUCPDCP-UHFFFAOYSA-N
• SMILES: O=C1c2c(O)cccc2-c2nn(CCNCCO)c3ccc(NCCNCCO)c1c23
• 折射率: 1.706

洛索蒽醌靶点实验

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实验名称：Inhibition of human topoisomerase 2alpha decantation activity 来源：ChEMBL 靶标：DNA topoisomerase 2-alpha External Id：CHEMBL967541

实验名称：Resistance factor, ratio of IC50 for etoposide-resistant human K/VP.5 cells to IC50 f... 来源：ChEMBL 靶标：K562 External Id：CHEMBL967540

实验名称：In vivo antitumor activity at a single dose of 12.5 mg/kg & 37.5 mg/kg total against ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL717383

实验名称：Binding affinity to calf thymus DNA assessed as change in thermal stability at 2 uM i... 来源：ChEMBL 靶标：DNA External Id：CHEMBL967537

实验名称：In vivo antitumor activity at a single dose of 6.5 mg/kg & 18.8 mg/kg total against m... 来源：ChEMBL 靶标：N/A External Id：CHEMBL717384

实验名称：Growth inhibition of etoposide-resistant human K/VP.5 cells after 72 hrs by MTS metho... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL967539

实验名称：In vivo antitumor activity at a single dose of 12.5 mg/kg & 37.5 mg/kg total against ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL717387

实验名称：Growth inhibition of human K562 cells after 72 hrs by MTS method 来源：ChEMBL 靶标：K562 External Id：CHEMBL967538

实验名称：In vivo antitumor activity against P388 leukemia cells at a dose of 25 mg/kg as a sin... 来源：ChEMBL 靶标：P388 External Id：CHEMBL757080

实验名称：In vivo antitumor activity at a single dose of 6.5 mg/kg & 18.8 mg/kg total against m... 来源：ChEMBL 靶标：N/A External Id：CHEMBL717388

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洛索蒽醌英文别名

• CI-941
• Anthra(1,9-cd)pyrazol-6(2H)-one,7-hydroxy-2-(2-((2-hydroxyethyl)amino)ethyl)-5-((2-((2-hydroxyethyl)amino)ethyl)amino)
• bianthrazole
• Losoxantrone [INN:BAN]
• 7-hydroxy-2-[2-[(2-hydroxyethyl)amino]ethyl]-5-[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthra[1,9-cd]pyrazol-6(2H)-one
• DuP-941
• Bis-alkylamino anthrapyrazole