JNJ-28312141

• 常用名: JNJ-28312141
• 英文名: JNJ-28312141
• CAS号: 885692-52-4
• 分子量: 460.571
• 密度: 1.3±0.1 g/cm3
• 沸点: N/A
• 分子式: C₂₆H₃₂N₆O₂
• 熔点: N/A
• 闪点: N/A

JNJ-28312141用途

JNJ-28312141 is an orally active CSF1R inhibitor (Colony-stimulating factor-1 receptor, CRF1R) and also a FLT3 inhibitor.

JNJ-28312141名称

• 英文名: 5-cyano-N-[2-(cyclohexen-1-yl)-4-[1-[2-(dimethylamino)acetyl]piperidin-4-yl]phenyl]-1H-imidazole-2-carboxamide

JNJ-28312141物理化学性质

• 密度: 1.3±0.1 g/cm3
• 分子式: C₂₆H₃₂N₆O₂
• 分子量: 460.571
• 精确质量: 460.258667
• PSA: 105.12000
• LogP: 2.72
• InChIKey: GUBJNPWVIUFSTR-UHFFFAOYSA-N
• SMILES: CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3ncc(C#N)[nH]3)c(C3=CCCCC3)c2)CC1
• 折射率: 1.632

JNJ-28312141靶点实验

查看更多实验

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Human KIT proto-oncogene receptor tyrosine kinase (Type III RTKs: PDGFR, CSFR, Kit, F... 来源：IUPHAR-DB 靶标：KIT proto-oncogene receptor tyrosine kinase (Type III RTKs: PDGFR, CSFR, Kit, FLT3 receptor family) [Homo sapiens] External Id：1805_Human

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-keats_OPM1-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-OC1MY5-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-KMS_34-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-keats_L363-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-keats_OCIMY7-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-MM1R-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-mm1s-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-KMS-28PE-m4-1

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JNJ-28312141英文别名

• 4-cyano-1H-imidazole-2-carboxylic acid {2-cyclohex-1-enyl-4-[1-(2-dimethylaminoacetyl)piperidin-4-yl]phenyl}amide
• 1H-Imidazole-2-carboxamide,5-cyano-n-(2-(1-cyclohexen-1-yl)-4-(1-(2-(dimethylamino)acetyl)-4-piperidinyl)phenyl)
• UNII-YKQ241VJ92
• 4-Cyano-N-{2-(1-cyclohexen-1-yl)-4-[1-(N,N-dimethylglycyl)-4-piperidinyl]phenyl}-1H-imidazole-2-carboxamide