2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-3-methylpyrimidin-4(3H)-one

• 常用名: 2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-3-methylpyrimidin-4(3H)-one
• 英文名: 2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-3-methylpyrimidin-4(3H)-one
• CAS号: 890019-50-8
• 分子量: 497.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₉H₂₄FN₃O₄
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-3-methylpyrimidin-4(3H)-one

物理化学性质

• 分子式: C₂₉H₂₄FN₃O₄
• 分子量: 497.5
• InChIKey: IKPJWGNTDNCFPS-UHFFFAOYSA-N
• SMILES: COc1cc2nccc(Oc3ccc(-c4cnc(Cc5ccccc5)n(C)c4=O)cc3F)c2cc1OC

靶点实验

查看更多实验

实验名称：Inhibition of human recombinant HGF-mediated cMet phosphorylation in human PC3 cells 来源：ChEMBL 靶标：Hepatocyte growth factor External Id：CHEMBL971823

实验名称：Inhibition of phosphorylated RON 来源：ChEMBL 靶标：Macrophage-stimulating protein receptor External Id：CHEMBL971822

实验名称：Inhibition of human recombinant HGF-mediated cMet phosphorylation in mouse CT26 cells 来源：ChEMBL 靶标：Hepatocyte growth factor External Id：CHEMBL971824

实验名称：Inhibition of IGFR 来源：ChEMBL 靶标：N/A External Id：CHEMBL971577

实验名称：Selectivity of cMet over KDR 来源：ChEMBL 靶标：N/A External Id：CHEMBL971819

实验名称：Experimentally measured binding affinity data (Ki) for protein-ligand complexes deriv... 来源：Shanghai Institute of Organic Chemistry 靶标：N/A External Id：PDBbind-Ki for protein-ligand complexes

实验名称：Inhibition of c-Met (unknown origin) 来源：ChEMBL 靶标：Hepatocyte growth factor receptor External Id：CHEMBL3594727

实验名称：Selectivity of cMet over IGFR 来源：ChEMBL 靶标：N/A External Id：CHEMBL971821

实验名称：Selectivity of cMet over RON 来源：ChEMBL 靶标：N/A External Id：CHEMBL971820

实验名称：Inhibition of phosphorylated KDR by HTRF assay 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 2 External Id：CHEMBL971817

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